Annulative allylic alkylation reactions between dual electrophiles and dual nucleophiles: applications in complex molecule synthesis

BM Trost, CA Kalnmals - Chemistry–A European Journal, 2020 - Wiley Online Library
Metal‐catalyzed allylic alkylation reactions between dual nucleophiles and dual
electrophiles represent a powerful set of methods for the synthesis of small‐, medium‐, and …

Palladium-catalyzed annulative allylic alkylation for regioselective construction of indole-fused medium-sized cyclic ethers

LQ Chen, CF Zhu, S Zhang, BY Liu, SJ Tu… - Chinese Chemical …, 2023 - Elsevier
A new palladium-catalyzed annulative allylic alkylation (AAA) reaction of 2-(indol-2-yl)
phenols with dual allylic electrophiles such as isobutylene dicarbonate and butene …

Syntheses and anti-HIV and human cluster of differentiation 4 (CD4) down-modulating potencies of pyridine-fused cyclotriazadisulfonamide (CADA) compounds

LA Lumangtad, E Claeys, S Hamal, A Intasiri… - Bioorganic & medicinal …, 2020 - Elsevier
CADA compounds selectively down-modulate human cell-surface CD4 protein and are of
interest as HIV entry inhibitors and as drugs for asthma, rheumatoid arthritis, diabetes and …

Reduction of Progranulin-induced breast Cancer stem cell propagation by Sortilin-targeting Cyclotriazadisulfonamide (CADA) compounds

K Berger, E Pauwels, G Parkinson… - Journal of medicinal …, 2021 - ACS Publications
Cyclotriazadisulfonamide (CADA) compounds selectively down-modulate two human
proteins of potential therapeutic interest, cluster of differentiation 4 (CD4) and sortilin …

Palladium-catalyzed [3+ 3] annulations of 1-alkyl-indolin-2-imines and dialkyl (2-methylenepropane-1, 3-diyl) dicarbonates

Y Li, J Jie, W Xiao, H Yang, H Fu - Organic Chemistry Frontiers, 2022 - pubs.rsc.org
Palladium-catalyzed [3+ 3] annulations of 1-alkyl-indolin-2-imines and dialkyl (2-
methylenepropane-1, 3-diyl) dicarbonates leading to pyrido [2, 3-b] indole derivatives have …

Investigating the Unique Mechanism of Action of CADA Analogs for Down-Modulating CD4, Sortilin, and ACE2

MA Islam - 2023 - search.proquest.com
The small molecule cyclotriazadisulfonamide (CADA) has been found to inhibit the
replication of human immunodeficiency virus (HIV) and human herpesvirus type 7 in cell …

Highly Stable and Conductive Anion Exchange Membranes for Fuel Cells

H Chen - 2023 - search.proquest.com
Anion exchange membranes (AEMs) have emerged as a promising technology for a range
of electrochemical devices, including fuel cells and electrolyzers. These membranes play a …

Total Synthesis of Imidazole-Containing β-Carboline Alkaloids and Pyrrole-Imidazole Alkaloids

MS Roy - 2021 - search.proquest.com
The first part in this dissertation focuses on the development of an enantioselective total
synthesis of villagorgin A, from another natural product haploscleridamine …

Total Synthesis of Imidazole-Containing β-Carboline Alkaloids and Pyrrole-Imidazole Alkaloids

M Singha Roy - 2021 - mavmatrix.uta.edu
The first part in this dissertation focuses on the development of an enantioselective total
synthesis of villagorgin A, from another natural product haploscleridamine …

Synthesis & Pharmacokinetic Evaluation of Cyclotriazadisulfonamide (CADA) Analogs to Target Signal Peptides

DE Jones - 2019 - search.proquest.com
The small molecule cyclotriazadisulfonamide (CADA) was found to down-modulate the
expression of the human cluster of differentiation 4 (hCD4) glycoprotein and sortilin through …