Abstract The coronavirus disease 2019 (COVID-19) pandemic has claimed millions of lives
and caused a global economic crisis. No effective antiviral drugs are currently available to …

Newly endocytosed integral cell surface proteins are typically either directed for degradation
or subjected to recycling back to the plasma membrane. The sorting of integral cell surface …

Endosomes are dynamic intracellular compartments that control the sorting of a constant
stream of different transmembrane cargos either for ESCRT‐mediated degradation or for …

The retromer complex has a well-established role in endosomal protein sorting, being
necessary for maintaining the dynamic localisation of hundreds of membrane proteins that …

Protein homeostasis is maintained by removing misfolded, damaged, or excess proteins and
damaged organelles from the cell by three major pathways; the ubiquitin-proteasome …

Aberrations in membrane trafficking pathways have profound effects in cellular dynamics of
cellular sorting processes and can drive severe physiological outcomes. Sorting nexin 27 …

During infection chlamydial pathogens form an intracellular membrane-bound replicative
niche termed the inclusion, which is enriched with bacterial transmembrane proteins called …

Biogenesis of viral replication organelles (VROs) is critical for replication of positive-strand
RNA viruses. In this work, we demonstrate that tomato bushy stunt virus (TBSV) and the …

Porcine deltacoronavirus (PDCoV) is an emerging swine enteropathogenic coronavirus with
the potential to infect humans. Accessory protein NS6, encoded by PDCoV, is a key factor …

The retromer complex (Vps35-Vps26-Vps29) is essential for endosomal membrane
trafficking and signaling. Mutation of the retromer subunit Vps35 causes late-onset …