[HTML][HTML] Synthesis and Structure of Novel Hybrid Compounds Containing Phthalazin-1(2H)-imine and 4,5-Dihydro-1H-imidazole Cores and Their Sulfonyl …

Ł Balewski, M Gdaniec, A Hering, C Furman… - International Journal of …, 2024 - mdpi.com
A novel hybrid compound—2-(4, 5-dihydro-1 H-imidazol-2-yl) phthalazin-1 (2 H)-imine (5)
was synthesized and converted into di-substituted sulfonamide derivatives 6a–o and …

Phthalazine Sulfonamide Derivatives as Carbonic Anhydrase Inhibitors. Synthesis, Biological and in silico Evaluation

A Angeli, A Petrou, VG Kartsev, A Zubenko… - …, 2024 - Wiley Online Library
Abstract Carbonic Anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze
the reversible hydration of carbon dioxide involved in several biological processes. They …