Traumatic brain injury (TBI) is the most common cause of death and disability in those aged
under 40 years in the UK. Higher rates of morbidity and mortality are seen in low-income …

Background Severe trauma represents a major global public health burden and the
management of post-traumatic bleeding continues to challenge healthcare systems around …

Globally, approximately 70 million people sustain traumatic brain injury each year and this
can have significant physical, psychosocial and economic consequences for patients, their …

Neutrophil extracellular traps (NETs) are complexes of decondensed DNA fibers and
antimicrobial peptides that are released by neutrophils and play important roles in many …

Background Pyroptosis, especially microglial pyroptosis, may play an important role in
central nervous system pathologies, including traumatic brain injury (TBI). Transplantation of …

Background Therapeutic hypothermia may need prolonged duration for the patients with
severe traumatic brain injury (sTBI). Methods The Long-Term Hypothermia trial was a …

The Australian Traumatic Brain Injury Initiative (AUS-TBI) is developing a data resource to
enable improved outcome prediction for people with moderate-severe TBI (msTBI) across …

Advancement of the prehospital and ED care that include stabilization of physiological
parameters, rapid correction of impaired coagulation, noninvasive techniques to identify …

Post-traumatic epilepsy (PTE) accounts for 5% of all epilepsies. The incidence of PTE after
traumatic brain injury (TBI) depends on the severity of injury, approaching one in three in …

Transient receptor potential (TRP) proteins form a superfamily of cation channels that are
expressed in a wide range of tissues and cell types. During the last years, great progress …