Abstract Chitinase‐3‐like protein 1 (CHI3L1) is a secreted glycoprotein characterized by its
ability to regulate multiple biological processes, such as the inflammatory response and …

Background Neurofilament light chain (NfL) in cerebrospinal fluid (CSF) is a biomarker of
multiple sclerosis (MS). However, CSF sampling is invasive and has limited the clinical …

Multiple sclerosis (MS) is an immune-mediated disease that targets the myelin sheath of
central nervous system (CNS) neurons leading to axon injury, neuronal death, and …

Importance Early treatment initiation in multiple sclerosis (MS) is crucial in preventing
irreversible neurological damage and disability progression. The current assessment of …

Multiple Sclerosis (MS) is a chronic autoimmune disease affecting the central nervous
system which is characterized by demyelinating lesions and axonal damage. MS is a …

A growing body of work points toward the existence of a clinically symptomatic prodromal
phase in multiple sclerosis (MS) that might span 5–10 years or more. A prodrome is an early …

Nowadays, there is a need for reliable fluid biomarkers to improve differential diagnosis,
prognosis, and the prediction of treatment response, particularly in the management of …

Introduction: Multiple Sclerosis (MS) is the most common immune-mediated chronic
neurodegenerative disease of the central nervous system (CNS) affecting young people …

Multiple sclerosis (MS) has been clinically considered a chronic inflammatory disease of the
white matter; however, in the last decade growing evidence supported an important role of …

Despite extensive research into the pathophysiology of multiple sclerosis (MS) and recent
developments in potent disease-modifying therapies (DMTs), two-thirds of relapsing …