Upon receipt in the dorsal horn (DH) of the spinal cord, nociceptive (pain-signalling)
information from the viscera, skin and other organs is subject to extensive processing by a …

The mammalian central nervous system possesses well-defined networks that modulate
nociceptive transmission. The most extensively studied are the networks that underlie …

Publisher Summary Considerable evidence suggests that the cell dense region surrounding
the midbrain aqueduct, the midbrain periaqueductal gray region (PAG), is a crucial neural …

Publisher Summary This chapter presents an overview of the caudal structures in brainstem
and spinal cord as far as they concern the motor system. It discusses a concept that …

The rostral ventromedial medulla is part of a neural network through which systemically
administered morphine produces antinociception. Two physiologically characterized classes …

Neurons in the rostroventromedial medulla (RVM) project to spinal loci where the neurons
inhibit or facilitate pain transmission. Abnormal activity of facilitatory processes may thus …

The fact that GABA receptor agonists and antagonists influence nociceptive thresholds when
microinjected into the rostroventral medulla or in the spinal cord may reflect the involvement …

Previous findings indicate that the brain stem descending system becomes more active in
modulating spinal nociceptive processes during the development of persistent pain. The …

Stimulation in the nucleus raphe magnus (NRM) inhibits transmissionof nociceptive
information within the spinal cord through activation of bulbospinal pathways. This study …

The rostral ventrolateral medulla oblongata plays an important role in the control of arterial
blood pressure and it has strong descending projections into the intermediolateral nucleus …