Hypertrophic cardiomyopathy is a myocardial disease defined by an increased left
ventricular wall thickness not solely explained by abnormal loading conditions. It is often …

Hypertrophic cardiomyopathy (HCM) is a common myocardial disease defined by increased
left ventricular wall thickness unexplained by loading conditions. It is frequently caused by …

Hypertrophic cardiomyopathy (HCM) is the major contributor to morbidity and mortality in
Noonan syndrome (NS). Gain-of-function variants in RAF1 are associated with high …

Hypertrophic cardiomyopathy (HCM) is a myocardial disorder characterized by left
ventricular (LV) hypertrophy, which cannot be entirely attributed to loading conditions such …

Introduction: The aim of this study was to evaluate the age at onset, clinical course, and
patterns of left ventricular (LV) remodelling during follow-up in children and young patients …

Noonan syndrome with multiple lentigines (NSML, formerly known as LEOPARD syndrome)
is a variant of Noonan syndrome which is an autosomal dominant disorder. Most cases of …

Abstract Noonan Syndrome with Multiple Lentigines (NSML-formerly known as LEOPARD
syndrome) is a rare autosomal dominant condition that usually exhibits cardiac involvement …

Cardiovascular disease is an important feature of the RASopathy disorders: Noonan, cardio-
facio-cutaneous, and Costello syndromes with significant implications for short-and long …

Noonan syndrome with multiple lentigines (NSML) is a RASopathy characterized by features
of multiple lentigines, ECG conduction abnormalities, ocular hypertelorism, pulmonary …

Noonan syndrome with multiple lentigines (NSML), previously known as LEOPARD
syndrome, is a rare autosomal dominant genetic disease with only over 200 reported cases …