Significance: Innate and adaptive immunity play fundamental roles in the development of
hypertension and its complications. As effectors of the cell-mediated immune response …

The spontaneously hypertensive rat (SHR) is one of the major models of hypertension. This
article describes the current state of knowledge about the mechanism behind kidney …

Ferulic acid is a simple phenolic acid commonly present in cereals. In this study, changes in
heart and kidney structure and function were measured in young N ω-nitro-L-arginine methyl …

The angiotensin II type 1 receptor (AT1R) mediates most hypertensive actions of angiotensin
II. To understand the molecular regulation of the AT1R in normal physiology and …

Objective Background The main cause of death among patients with malignant hypertension
is a kidney failure. The promising field in essential and malignant hypertension therapy …

Renal T-cell infiltration is a key component of salt-sensitive hypertension in Dahl salt-
sensitive (SS) rats. Here, we use an electronic servo-control technique to determine the …

Humans are constantly exposed to low concentrations of ubiquitous environmental pollutant,
Bisphenol A (BPA). Due to the prevalence of hypertension (one of the major risk factors of …

Objective: Hypertension is associated with an increased cancer mortality and a higher
kidney cancer risk. Blood pressure regulating hormones, such as the peptide hormone …

BACKGROUND The development of renal fibrosis is a consequence of arterial
hypertension. L-carnitine plays an essential role in the β-oxidation of fatty acids, and we …

Reduced glomerular filtration, hypertension and renal microvascular injury are hallmarks of
chronic kidney disease, which has a global prevalence of~ 10%. We have shown previously …