Purpose Loss of skeletal muscle mass, also known as muscle wasting or muscle atrophy, is
a common symptom of several chronic diseases, such as cancer and infectious diseases …

Maple syrup urine disease (MSUD) is a metabolic disease caused by a deficiency in the
branched-chain α-keto acid dehydrogenase complex, leading to the accumulation of …

To investigate anti-arthritic activity of luteolin (Lut) in Freund's complete adjuvant (FCA)-
induced arthritis (AA) in rats. AA was induced by injecting with Freund's complete adjuvant …

Our study aimed to evaluate the analgesic and antioxidant effects of ginger (Zingiber
officinale) root capsule extract (GRCE) in addition to diclofenac (D) sodium treatment in …

In the present study, we show that an aqueous extract of Arbutus unedo L.(AuE), a
Mediterranean endemic plant widely employed as an astringent, diuretic and urinary anti …

The citrus flavonoid hesperidin has been reported to possess a wide range of
pharmacological properties. We have investigated the preventive and therapeutic effects of …

The clinical application of cyclosporine A (CsA) as an immunosuppressive agent is limited
by its organ toxicity. We aimed to evaluate the effectiveness of α-lipoic acid against CsA …

Rheumatoid arthritis (RA) is a systemic inflammatory disease with cardiovascular
complications as the leading cause of morbidity. Carvedilol is an adrenergic antagonist …

Animal models of rheumatoid arthritis (RA) are widely used for testing potential new
therapies for RA. The most commonly used models of human RA are adjuvant-induced …

Numerous lines of evidence suggest that heterocyclic compounds used as analgesic, anti-
inflammatory and anti-migraine agents can be potent regulators of the nitroxidative stress …