Salivary glands produce and secrete saliva, which is essential for maintaining oral health
and overall health. Understanding both the unique structure and physiological function of …

The neural crest (NC) is a transient, multipotent and migratory cell population that generates
an astonishingly diverse array of cell types during vertebrate development. These cells …

Diagnose oral diseases quickly and accurately! Oral Pathology: Clinical Pathologic
Correlations, 7th Edition presents diseases and conditions by appearance and presentation …

We report a genome-wide association scan for facial features in∼ 6,000 Latin Americans.
We evaluated 14 traits on an ordinal scale and found significant association (P values< 5× …

An international advisory group met at the National Institutes of Health in Bethesda,
Maryland in 2017, to discuss a new classification system for the ectodermal dysplasias …

An adaptive variant of the human Ectodysplasin receptor, EDARV370A, is one of the
strongest candidates of recent positive selection from genome-wide scans. We have …

Background Dental agenesis is the most common, often heritable, developmental anomaly
in humans. Mutations in MSX1, PAX9, AXIN2 and the ectodermal dysplasia genes EDA …

The human body is covered with several million sweat glands. These tiny coiled tubular skin
appendages produce the sweat that is our primary source of cooling and hydration of the …

INTRODUCTION Across the vertebrate kingdom, epithelial appendages—including
mammary, sweat, and salivary glands; hair follicles (HFs); teeth; scales; and feathers—begin …

Human WNT10A mutations are associated with developmental tooth abnormalities and
adolescent onset of a broad range of ectodermal defects. Here we show that β-catenin …