Ischemic Stroke Risk in Patients With Nonvalvular Atrial Fibrillation: JACC Review Topic of the Week

M Alkhouli, PA Friedman - Journal of the American College of Cardiology, 2019 - jacc.org
The last decade has witnessed remarkable advances in pharmacological and
nonpharmacological strategies for stroke prevention in patients with atrial fibrillation …

Left atrial evaluation by cardiovascular magnetic resonance: sensitive and unique biomarkers

DC Peters, J Lamy, AJ Sinusas… - European Heart …, 2022 - academic.oup.com
Left atrial (LA) imaging is still not routinely used for diagnosis and risk stratification, although
recent studies have emphasized its importance as an imaging biomarker. Cardiovascular …

Demonstration of patient-specific simulations to assess left atrial appendage thrombogenesis risk

M García-Villalba, L Rossini, A Gonzalo… - Frontiers in …, 2021 - frontiersin.org
Atrial fibrillation (AF) alters left atrial (LA) hemodynamics, which can lead to thrombosis in
the left atrial appendage (LAA), systemic embolism and stroke. A personalized risk …

Deep Learning Framework for Real-Time Estimation of in-silico Thrombotic Risk Indices in the Left Atrial Appendage

X Morales Ferez, J Mill, KA Juhl, C Acebes… - Frontiers in …, 2021 - frontiersin.org
Patient-specific computational fluid dynamics (CFD) simulations can provide invaluable
insight into the interaction of left atrial appendage (LAA) morphology, hemodynamics, and …

[HTML][HTML] Pulmonary vein flow split effects in patient-specific simulations of left atrial flow

E Durán, M García-Villalba, P Martínez-Legazpi… - Computers in biology …, 2023 - Elsevier
Disruptions to left atrial (LA) blood flow, such as those caused by atrial fibrillation (AF), can
lead to thrombosis in the left atrial appendage (LAA) and an increased risk of systemic …

[PDF][PDF] 心房颤动患者左心房形态结构及功能与血栓形成关系的研究进展

杨敏, 肖模超 - 临床心血管病杂志, 2023 - lcxxg.whuhzzs.com
心房颤动(房颤) 是最常见的心律失常之一, 而血栓事件是房颤患者最严重的并发症.
目前临床上主要通过CHA2DS2-VASc 评分指导抗凝治疗, 但有较多不足. 有研究发现左心房的 …

Joint analysis of morphological parameters and in silico haemodynamics of the left atrial appendage for thrombogenic risk assessment

MI Pons, J Mill, A Fernandez-Quilez… - Journal of …, 2022 - Wiley Online Library
Background. Atrial fibrillation (AF) is considered the most common human arrhythmia. In
nonvalvular AF, around 99% of thrombi are formed in the left atrial appendage (LAA) …

The role of the pulmonary veins on left atrial flow patterns and thrombus formation

J Mill, J Harrison, M Saiz-Vivo, C Albors, X Morales… - Scientific Reports, 2024 - nature.com
Atrial fibrillation (AF) is the most common human arrhythmia, forming thrombi mostly in the
left atrial appendage (LAA). However, the relation between LAA morphology, blood patterns …

The role of patient-specific morphological features of the left atrial appendage on the thromboembolic risk under atrial fibrillation

G Musotto, A Monteleone, D Vella… - Frontiers in …, 2022 - frontiersin.org
Background A large majority of thrombi causing ischemic complications under atrial
fibrillation (AF) originate in the left atrial appendage (LAA), an anatomical structure departing …

Diagnosis and management of cardioembolic stroke

S Yaghi - CONTINUUM: Lifelong Learning in Neurology, 2023 - journals.lww.com
OBJECTIVE Cardioembolic stroke accounts for nearly 30% of ischemic strokes. Prompt
diagnosis of the underlying mechanism may improve secondary prevention strategies. This …