Inhalable particulate drug delivery systems for lung cancer therapy: Nanoparticles, microparticles, nanocomposites and nanoaggregates

HM Abdelaziz, M Gaber, MM Abd-Elwakil… - Journal of Controlled …, 2018 - Elsevier
There is progressive evolution in the use of inhalable drug delivery systems (DDSs) for lung
cancer therapy. The inhalation route offers many advantages, being non-invasive method of …

A detailed insight of the tumor targeting using nanocarrier drug delivery system

S Batool, S Sohail, F ud Din, AH Alamri… - Drug Delivery, 2023 - Taylor & Francis
Human struggle against the deadly disease conditions is continued since ages. The
contribution of science and technology in fighting against these diseases cannot be ignored …

Harnessing inhaled nanoparticles to overcome the pulmonary barrier for respiratory disease therapy

Z Jin, Q Gao, K Wu, J Ouyang, W Guo… - Advanced Drug Delivery …, 2023 - Elsevier
The lack of effective treatments for pulmonary diseases presents a significant global health
burden, primarily due to the challenges posed by the pulmonary barrier that hinders drug …

[HTML][HTML] Cancer therapy with phytochemicals: evidence from clinical studies

A Hosseini, A Ghorbani - Avicenna journal of phytomedicine, 2015 - ncbi.nlm.nih.gov
Cancer is still one of the major causes of mortality in both developing and developed
countries. At present, in spite of intensive interventions, a large number of patients suffer …

[HTML][HTML] Nanotechnology approaches for inhalation treatment of lung diseases

A Kuzmov, T Minko - Journal of controlled release, 2015 - Elsevier
Local administration of therapeutics by inhalation for treatment of lung diseases has the
ability to deliver drugs, nucleic acids and peptides specifically to the site of their action and …

Nano-delivery to the lung-by inhalation or other routes and why nano when micro is largely sufficient?

V Forest, J Pourchez - Advanced Drug Delivery Reviews, 2022 - Elsevier
Respiratory diseases gather a wide range of disorders which are generally difficult to treat,
partly due to a poor delivery of drugs to the lung with adequate dose and minimum side …

[HTML][HTML] Pharmaceutical strategies to extend pulmonary exposure of inhaled medicines

Y Guo, H Bera, C Shi, L Zhang, D Cun… - Acta Pharmaceutica Sinica …, 2021 - Elsevier
Pulmonary administration route has been extensively exploited for the treatment of local
lung diseases such as asthma, chronic obstructive pulmonary diseases and respiratory …

Applications and advancements of nanoparticle-based drug delivery in alleviating lung cancer and chronic obstructive pulmonary disease

G De Rubis, KR Paudel, L Corrie, S Mehndiratta… - Naunyn-Schmiedeberg's …, 2024 - Springer
Lung cancer (LC) and chronic obstructive pulmonary disease (COPD) are among the
leading causes of mortality worldwide. Cigarette smoking is among the main aetiologic …

Nanomedicine in pulmonary delivery

HM Mansour, YS Rhee, X Wu - International journal of …, 2009 - Taylor & Francis
The lung is an attractive target for drug delivery due to noninvasive administration via
inhalation aerosols, avoidance of first-pass metabolism, direct delivery to the site of action …

Inhaled nanoparticles–An updated review

T Praphawatvet, JI Peters, RO Williams III - International journal of …, 2020 - Elsevier
We are providing an update to our previously published review paper on inhaled
nanoparticles, thus updating with the most recent reports in the literature. The field of …