Strategies for nonviral nanoparticle‐based delivery of CRISPR/Cas9 therapeutics

F Chen, M Alphonse, Q Liu - Wiley Interdisciplinary Reviews …, 2020 - Wiley Online Library
CRISPR‐based genome editing technology has become an important potential therapeutic
tool for various diseases. A vital challenge is to reach a safe, efficient, and clinically suitable …

Recent advances in phytochemical based nano-drug delivery systems to combat breast cancer: A review

R Solanki, B Jodha, KE Prabina, N Aggarwal… - Journal of Drug Delivery …, 2022 - Elsevier
Breast Cancer is the most common cancer in women worldwide. Recently bioactive plant
products, namely phytochemicals are being been explored by researchers for their …

A comparison of models for the analysis of the kinetics of drug release from PLGA-based nanoparticles

LP Jahromi, M Ghazali, H Ashrafi, A Azadi - Heliyon, 2020 - cell.com
Purpose Poly (lactic-co-glycolic acid) has received much academic attention for developing
nanotherapeutics and FDA has approved it for several applications. An important parameter …

Nanocarrier-mediated chemo-immunotherapy arrested cancer progression and induced tumor dormancy in desmoplastic melanoma

Q Liu, F Chen, L Hou, L Shen, X Zhang, D Wang… - ACS …, 2018 - ACS Publications
In desmoplastic melanoma, tumor cells and tumor-associated fibroblasts are the major
dominators playing a critical role in the fibrosis morphology as well as the …

Evodiamine: A review of its pharmacology, toxicity, pharmacokinetics and preparation researches

Q Sun, L Xie, J Song, X Li - Journal of Ethnopharmacology, 2020 - Elsevier
Ethnopharmacological relevance Evodia rutaecarpa, a well-known herb medicine in China,
is extensively applied in traditional Chinese medicine (TCM). The plant has the effects of …

Natural compounds-based nanomedicines for cancer treatment: Future directions and challenges

T Andreani, R Cheng, K Elbadri, C Ferro… - Drug Delivery and …, 2024 - Springer
Several efforts have been extensively accomplished for the amelioration of the cancer
treatments using different types of new drugs and less invasives therapies in comparison …

Folate functionalized and evodiamine‐loaded pluronic nanomicelles for augmented cervical cancer cell killing

R Solanki, AK Jangid, M Jadav… - Macromolecular …, 2023 - Wiley Online Library
Evodiamine (Evo) is a natural, biologically active plant alkaloid with wide range of
pharmacological activities. In the present study Evo‐loaded folate‐conjugated Pluronic F108 …

Enhancing apoptosis-mediated anticancer activity of evodiamine through protein-based nanoparticles in breast cancer cells

R Solanki, PK Rajput, B Jodha, UCS Yadav, S Patel - Scientific Reports, 2024 - nature.com
In the cutting-edge era of developing precision therapeutics, nanoparticles have emerged as
a potent drug delivery system. Altering the size of poorly water-soluble drugs to nanoscale …

Natural product evodiamine-inspired medicinal chemistry: Anticancer activity, structural optimization and structure-activity relationship

Z Wang, Y Xiong, Y Peng, X Zhang, S Li, Y Peng… - European Journal of …, 2023 - Elsevier
It is a well-known phenomenon that natural products can serve as powerful drug leads to
generate new molecular entities with novel therapeutic utility. Evodiamine (Evo), a major …

Evodiamine as an anticancer agent: a comprehensive review on its therapeutic application, pharmacokinetic, toxicity, and metabolism in various cancers

M Panda, SK Tripathi, G Zengin, BK Biswal - Cell Biology and Toxicology, 2023 - Springer
Evodiamine is a major alkaloid component found in the fruit of Evodia rutaecarpa. It shows
the anti-proliferative potential against a wide range of cancers by suppressing cell growth …