Age-related cataracts: Role of unfolded protein response, Ca2+ mobilization, epigenetic DNA modifications, and loss of Nrf2/Keap1 dependent cytoprotection
P Periyasamy, T Shinohara - Progress in Retinal and Eye Research, 2017 - Elsevier
Age-related cataracts are closely associated with lens chronological aging, oxidation,
calcium imbalance, hydration and crystallin modifications. Accumulating evidence indicates …
calcium imbalance, hydration and crystallin modifications. Accumulating evidence indicates …
[PDF][PDF] Advances in the mechanism of paraquat-induced pulmonary injury
B Sun, YG Chen - Eur Rev Med Pharmacol Sci, 2016 - europeanreview.org
MATERIALS AND METHODS: The mechanism of PQ-induced pulmonary injury was
elucidated through both literature review and experimentation. RESULTS: As an effective …
elucidated through both literature review and experimentation. RESULTS: As an effective …
Paraquat affects mitochondrial bioenergetics, dopamine system expression, and locomotor activity in zebrafish (Danio rerio)
XH Wang, CL Souders II, YH Zhao, CJ Martyniuk - Chemosphere, 2018 - Elsevier
The dipyridyl herbicide paraquat induces oxidative stress in cells and is implicated in adult
neurodegenerative diseases. However, less is known about paraquat toxicity in early stages …
neurodegenerative diseases. However, less is known about paraquat toxicity in early stages …
Curcumin attenuates paraquat-induced cell death in human neuroblastoma cells through modulating oxidative stress and autophagy
T Jaroonwitchawan, N Chaicharoenaudomrung… - Neuroscience …, 2017 - Elsevier
Paraquat is a neurotoxic agent, and oxidative stress plays an important role in neuronal cell
death after paraquat exposure. In this study, we assessed the neuroprotective effect of …
death after paraquat exposure. In this study, we assessed the neuroprotective effect of …
[HTML][HTML] Enantioselective bioaccumulation and toxicity of the novel chiral antifungal agrochemical penthiopyrad in zebrafish (Danio rerio)
B Ren, T Zhao, Y Li, H Liang, Y Zhao, H Chen… - Ecotoxicology and …, 2021 - Elsevier
Succinate dehydrogenase inhibitor (SDHI) fungicides has been extensively used in
agricultural production, which are not easily degrade in the environment and have various …
agricultural production, which are not easily degrade in the environment and have various …
Klotho Alleviates Lung Injury Caused by Paraquat via Suppressing ROS/P38 MAPK‐Regulated Inflammatory Responses and Apoptosis
Z Zhang, Q Nian, G Chen, S Cui… - … medicine and cellular …, 2020 - Wiley Online Library
Acute lung injury (ALI) induced by paraquat (PQ) progresses rapidly with high mortality;
however, there is no effective treatment, and the specific mechanism is not well understood …
however, there is no effective treatment, and the specific mechanism is not well understood …
Ultrafine silicon dioxide nanoparticles cause lung epithelial cells apoptosis via oxidative stress-activated PI3K/Akt-mediated mitochondria-and endoplasmic reticulum …
Abstract Silicon dioxide nanoparticles (SiO2NPs) are widely applied in industry, chemical,
and cosmetics. SiO2NPs is known to induce pulmonary toxicity. In this study, we investigated …
and cosmetics. SiO2NPs is known to induce pulmonary toxicity. In this study, we investigated …
Oxaloacetate acid ameliorates paraquat-induced acute lung injury by alleviating oxidative stress and mitochondrial dysfunction
W Li, M Li, K Chen, Y Tang, R Yin, L Lan… - Frontiers in …, 2022 - frontiersin.org
Acute lung injury (ALI) is the primary cause of death among patients with acute paraquat
(PQ) poisoning, whereby peroxidative damage is an important mechanism underlying PQ …
(PQ) poisoning, whereby peroxidative damage is an important mechanism underlying PQ …
Hepatotoxicity of paraquat on common carp (Cyprinus carpio L.)
J Ma, Y Li, W Li, X Li - Science of the total environment, 2018 - Elsevier
Paraquat (PQ) is a nonselective herbicide that is used worldwide and has been
demonstrated to be a high risk to aquatic organisms. However, relatively little is known about …
demonstrated to be a high risk to aquatic organisms. However, relatively little is known about …
Lipid peroxidation end product 4-hydroxy-trans-2-nonenal triggers unfolded protein response and heme oxygenase-1 expression in PC12 cells: Roles of ROS and …
This study investigates the roles of ROS overproduction and MAPK signaling pathways in
the induction of unfolded protein response (UPR) and the expression of Phase II enzymes in …
the induction of unfolded protein response (UPR) and the expression of Phase II enzymes in …