Norovirus MLKL-like protein initiates cell death to induce viral egress

G Wang, D Zhang, RC Orchard, DC Hancks, TA Reese - Nature, 2023 - nature.com
Non-enveloped viruses require cell lysis to release new virions from infected cells,
suggesting that these viruses require mechanisms to induce cell death. Noroviruses are one …

Astrovirus replication in human intestinal enteroids reveals multi-cellular tropism and an intricate host innate immune landscape

AO Kolawole, C Mirabelli, DR Hill, SA Svoboda… - PLoS …, 2019 - journals.plos.org
Human astroviruses (HAstV) are understudied positive-strand RNA viruses that cause
gastroenteritis mostly in children and the elderly. Three clades of astroviruses, classic, MLB …

Inactivation of murine norovirus and fecal coliforms by ferrate (VI) in secondary effluent wastewater

K Manoli, R Maffettone, VK Sharma… - Environmental …, 2019 - ACS Publications
Ferrate (VI)(FeVIO42, Fe (VI)) is an emerging oxidant/disinfectant to treat a wide range of
contaminants and microbial pollutants in wastewater. This study describes the inactivation of …

Inactivation of murine norovirus and hepatitis A virus on fresh raspberries by gaseous ozone treatment

A Brié, N Boudaud, A Mssihid, J Loutreul, I Bertrand… - Food …, 2018 - Elsevier
Raspberries are vulnerable products for which industrial treatment solutions ensuring both
food safety and sensory quality are not easily applicable. Raspberries have been associated …

Viral replication complexes are targeted by LC3-guided interferon-inducible GTPases

SB Biering, J Choi, RA Halstrom, HM Brown… - Cell host & …, 2017 - cell.com
All viruses with positive-sense RNA genomes replicate on membranous structures in the
cytoplasm called replication complexes (RCs). RCs provide an advantageous …

Murine norovirus infection induces TH1 inflammatory responses to dietary antigens

R Bouziat, SB Biering, E Kouame, KA Sangani… - Cell host & …, 2018 - cell.com
Intestinal reovirus infection can trigger T helper 1 (TH 1) immunity to dietary antigen, raising
the question of whether other viruses can have a similar impact. Here we show that the …

[HTML][HTML] Membrane alterations induced by nonstructural proteins of human norovirus

SY Doerflinger, M Cortese, I Romero-Brey… - PLoS …, 2017 - journals.plos.org
Human noroviruses (huNoV) are the most frequent cause of non-bacterial acute
gastroenteritis worldwide, particularly genogroup II genotype 4 (GII. 4) variants. The viral …

The common mouse protozoa Tritrichomonas muris alters mucosal T cell homeostasis and colitis susceptibility

NK Escalante, P Lemire… - Journal of Experimental …, 2016 - rupress.org
The mammalian gastrointestinal tract hosts a diverse community of microbes including
bacteria, fungi, protozoa, helminths, and viruses. Through coevolution, mammals and these …

Molecular mechanism of RIPK1 and caspase-8 in homeostatic type I interferon production and regulation

Y Wang, R Karki, R Mall, BR Sharma, RC Kalathur… - Cell reports, 2022 - cell.com
Type I interferons (IFNs) are essential innate immune proteins that maintain tissue
homeostasis through tonic expression and can be upregulated to drive antiviral resistance …

Performic acid disinfection of municipal secondary effluent wastewater: inactivation of murine norovirus, fecal coliforms, and enterococci

R Maffettone, K Manoli, D Santoro… - Environmental …, 2020 - ACS Publications
Performic acid (PFA) is an emerging disinfectant to inactivate bacterial and viral
microorganisms in wastewater. In this study, the inactivation kinetics of murine norovirus …