[HTML][HTML] Nanoscale surface coatings and topographies for neural interfaces

Y Cho, Y Choi, H Seong - Acta Biomaterialia, 2024 - Elsevier
With the lack of minimally invasive tools for probing neuronal systems across spatiotemporal
scales, understanding the working mechanism of the nervous system and limited …

Biomaterials for local, controlled drug delivery to the injured spinal cord

AM Ziemba, RJ Gilbert - Frontiers in pharmacology, 2017 - frontiersin.org
Affecting approximately 17,000 new people each year, spinal cord injury (SCI) is a
devastating injury that leads to permanent paraplegia or tetraplegia. Current …

In vitro and in vivo evaluation of chitosan-alginate/gentamicin wound dressing nanofibrous with high antibacterial performance

HR Bakhsheshi-Rad, Z Hadisi, AF Ismail, M Aziz… - Polymer Testing, 2020 - Elsevier
Wound dressings based on nanofiber polymer scaffolds with good antimicrobial
performance and skin reconstruction ability are promising options to thwart wound infection …

Bioactive antibacterial bilayer PCL/gelatin nanofibrous scaffold promotes full-thickness wound healing

A Jafari, A Amirsadeghi, S Hassanajili… - International journal of …, 2020 - Elsevier
Abstract Treatment of diabetic, chronic, and full-thickness wounds is a challenge as these
injuries usually lead to infections that cause delayed and inappropriate healing. Therefore …

Injectable, magnetically orienting electrospun fiber conduits for neuron guidance

CDL Johnson, D Ganguly, JM Zuidema… - … applied materials & …, 2018 - ACS Publications
Magnetic electrospun fibers are of interest for minimally invasive biomaterial applications
that also strive to provide cell guidance. Magnetic electrospun fibers can be injected and …

Enhanced antibacterial activity of PEO-chitosan nanofibers with potential application in burn infection management

S Abid, T Hussain, A Nazir, A Zahir… - International journal of …, 2019 - Elsevier
Chitosan (CS) is a well-known biological macromolecule having numerous applications due
to its exceptional properties especially in the form of nanofibers. The antibacterial activity is …

Biomimetic extracellular matrix nanofibers electrospun with Calreticulin promote synergistic activity for tissue regeneration

ME Stack, S Mishra… - … Applied Materials & …, 2022 - ACS Publications
In recognition of the potential of calreticulin (CRT) protein in enhancing the rate and quality
of wound healing in excisional animal wound models, this study was to incorporate CRT via …

TGFβ3 is neuroprotective and alleviates the neurotoxic response induced by aligned poly-l-lactic acid fibers on naïve and activated primary astrocytes

MK Gottipati, AR D'Amato, AM Ziemba, PG Popovich… - Acta biomaterialia, 2020 - Elsevier
Following spinal cord injury, astrocytes at the site of injury become reactive and exhibit a
neurotoxic (A1) phenotype, which leads to neuronal death. In addition, the glial scar, which …

Electrospun fiber scaffolds for engineering glial cell behavior to promote neural regeneration

DL Puhl, JL Funnell, DW Nelson, MK Gottipati… - Bioengineering, 2020 - mdpi.com
Electrospinning is a fabrication technique used to produce nano-or micro-diameter fibers to
generate biocompatible, biodegradable scaffolds for tissue engineering applications …

Harnessing stem cells and biomaterials to promote neural repair

KF Bruggeman, N Moriarty, E Dowd… - British journal of …, 2019 - Wiley Online Library
With the limited capacity for self‐repair in the adult CNS, efforts to stimulate quiescent stem
cell populations within discrete brain regions, as well as harness the potential of stem cell …