Therapeutic strategies for COVID-19: progress and lessons learned
G Li, R Hilgenfeld, R Whitley, E De Clercq - Nature Reviews Drug …, 2023 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic has stimulated tremendous
efforts to develop therapeutic strategies that target severe acute respiratory syndrome …
efforts to develop therapeutic strategies that target severe acute respiratory syndrome …
Overview of immunological & virological factors driving the evolution & global spread of SARS-CoV-2 variants
R Ramasamy - Indian Journal of Medical Research, 2023 - journals.lww.com
Abstract The SARS-CoV-2, a highly infectious positive strand RNA virus first identified in
December 2019, has produced multiple genetic variants that have rapidly and sequentially …
December 2019, has produced multiple genetic variants that have rapidly and sequentially …
Pharmacological potential of Withania somnifera (L.) Dunal and Tinospora cordifolia (Willd.) Miers on the experimental models of COVID-19, T cell differentiation …
Cytokine release syndrome (CRS) due to severe acute respiratory coronavirus-2 (SARS-
CoV-2) infection leads to life-threatening pneumonia which has been associated with …
CoV-2) infection leads to life-threatening pneumonia which has been associated with …
Omicron sub-lineage BA. 5 infection results in attenuated pathology in hACE2 transgenic mice
A recently emerged sub-lineage of Omicron, BA. 5, together with BA. 4, caused a fifth wave
of coronavirus disease (COVID-19) in South Africa and subsequently emerged as a …
of coronavirus disease (COVID-19) in South Africa and subsequently emerged as a …
Evaluation of ayush-64 (a polyherbal formulation) and its ingredients in the Syrian hamster model for SARS-CoV-2 infection reveals the preventative potential of …
In the current study, we evaluated the efficacy of Ayush-64 (A64), a polyherbal formulation
containing Alstonia scholaris (L.) R. Br.(A. scholaris), Caesalpinia crista L.(C. crista) …
containing Alstonia scholaris (L.) R. Br.(A. scholaris), Caesalpinia crista L.(C. crista) …
Clinical and experimental evidence suggest omicron variant of SARS-CoV-2 is inherently less pathogenic than delta variant independent of previous immunity
Objectives To study clinical disease outcomes in both human and animal models to
understand the pathogenicity of omicron compared to the delta variant. Methods In this cross …
understand the pathogenicity of omicron compared to the delta variant. Methods In this cross …
[HTML][HTML] Exploring the potential of broadly neutralizing antibodies for treating SARS-CoV-2 variants of global concern in 2023: a comprehensive clinical review
SD Gutlapalli, VDP Ganipineni, S Danda, D Fabian… - Cureus, 2023 - ncbi.nlm.nih.gov
In the aftermath of the coronavirus disease 2019 (COVID-19) pandemic, the world is still
seeing outbreaks of COVID-19 infections as of 2023, especially in populations that have …
seeing outbreaks of COVID-19 infections as of 2023, especially in populations that have …
Optimized high-yield expression of envelope glycoprotein domain III from dengue virus serotypes 1 to 4
D Mallick, V Tyagi, A Saroj, M Bhutkar, V Kumar, M Das… - Biochimie, 2024 - Elsevier
Dengue virus (DENV) envelope glycoprotein Domain III (EDIII) is critical for viral entry, highly
immunogenic, and induces robust neutralizing antibody response. It is a prominent …
immunogenic, and induces robust neutralizing antibody response. It is a prominent …
SARS‐CoV‐2 infection induces thymic atrophy mediated by IFN‐γ in hACE2 transgenic mice
Pathogenic infections cause thymic atrophy, perturb thymic T‐cell development, and alter
immunological response. Previous studies reported dysregulated T‐cell function and …
immunological response. Previous studies reported dysregulated T‐cell function and …