Among the various expression systems employed for the over-production of proteins,
bacteria still remains the favorite choice of a Protein Biochemist. However, even today, due …

Eukaryotic membrane proteins, many of which are key players in various biological
processes, constitute more than half of the drug targets and represent important candidates …

DNA damage induced by reactive carbonyls (mainly methylglyoxal and glyoxal), called DNA
glycation, is quantitatively as important as oxidative damage. DNA glycation is associated …

Haloacid dehalogenase (HAD)-like hydrolases are a vast superfamily of largely
uncharacterized enzymes, with a few members shown to possess phosphatase, β …

Atopic dermatitis (AD) and chronic urticaria (CU) are common skin diseases with an
increasing prevalence and pathogenesis that are not fully understood. Emerging evidence …

Cystic fibrosis (CF) is one of the most common, yet fatal genetic diseases in Caucasians.
The presence of a defective CF transmembrane conductance regulator and the massive …

The multiligand receptor for advanced glycation end products (RAGE) of the Ig superfamily
transduces the biological impact of discrete families of ligands, including advanced glycation …

Bacteria such as Escherichia coli are frequently grown to high density to produce
biomolecules for study in the laboratory. To achieve this, cells can be incubated in extremely …

Background Non-enzymatic glycation is the addition of free carbonyl group of reducing
sugar to the free amino groups of proteins, resulting in the formation of a Schiff base and an …

The aim of this study was to compare the kinetics of the glycoxidation of bovine serum
albumin (BSA) as a model protein by three sugars: glucose, fructose and ribose, using …