[HTML][HTML] Nanoplastics toxicity specific to liver in inducing metabolic dysfunction—A comprehensive review
Plastic pollution in the world is widespread and growing. The environment is swamped with
nanoplastics (< 100 nm), and the health consequences of these less visible pollutants are …
nanoplastics (< 100 nm), and the health consequences of these less visible pollutants are …
Donafenib and GSK‐J4 synergistically induce ferroptosis in liver cancer by upregulating HMOX1 expression
C Zheng, B Zhang, Y Li, K Liu, W Wei… - Advanced …, 2023 - Wiley Online Library
Hepatocellular carcinoma (HCC) is one of the most lethal cancers worldwide. Donafenib is a
multi‐receptor tyrosine kinase inhibitor approved for the treatment of patients with advanced …
multi‐receptor tyrosine kinase inhibitor approved for the treatment of patients with advanced …
[HTML][HTML] FOXK2 affects cancer cell response to chemotherapy by promoting nucleotide de novo synthesis
Y Li, J Chen, B Wang, Z Xu, C Wu, J Ma, Q Song… - Drug Resistance …, 2023 - Elsevier
Aims Nucleotide de novo synthesis is essential to cell growth and survival, and its
dysregulation leads to cancers and drug resistance. However, how this pathway is …
dysregulation leads to cancers and drug resistance. However, how this pathway is …
Engineered tumor microvesicles modified by SP94 peptide for arsenic trioxide targeting drug delivery in liver cancer therapy
F Raza, M Zheng, H Zhong, J Su, B He, WE Yuan… - Biomaterials …, 2023 - Elsevier
Liver cancer is among the leading cause of cancer related death worldwide. There is
growing interest in using traditional Chinese medicines such as arsenic trioxide (ATO) to …
growing interest in using traditional Chinese medicines such as arsenic trioxide (ATO) to …
Genome‐wide CRISPR/Cas9 library screening revealed dietary restriction of glutamine in combination with inhibition of pyruvate metabolism as effective liver cancer …
Hepatocellular carcinoma (HCC) is the second most lethal cancer worldwide. Glutamine is
an essential, extracellular nutrient which supports HCC growth. Dietary glutamine deficiency …
an essential, extracellular nutrient which supports HCC growth. Dietary glutamine deficiency …
CRISPR in Targeted Therapy and Adoptive T Cell Immunotherapy for Hepatocellular Carcinoma
Despite recent therapeutic advancements, outcomes for advanced hepatocellular carcinoma
(HCC) remain unsatisfactory, highlighting the need for novel treatments. The CRISPR …
(HCC) remain unsatisfactory, highlighting the need for novel treatments. The CRISPR …
[HTML][HTML] Construction of a ceRNA regulatory network to explore potential pathogenesis mechanisms involved in human hepatocellular carcinoma
Y Liu, Z Dong, WJ Chen, L Chen, L Ju, W Cai, X Luo… - Scientific Reports, 2023 - nature.com
Worldwide, primary liver cancer is the third leading cause of cancer-related death.
Hepatocellular carcinoma (HCC) accounts for the majority of primary liver cancers. Recent …
Hepatocellular carcinoma (HCC) accounts for the majority of primary liver cancers. Recent …
Integrated transcriptomics and metabolomics analyses to investigate the anticancer mechanisms of cinobufagin against liver cancer through interfering with lipid …
A Yang, Q Wu, A Wang, Q Chen, J Yang, Y Tao… - Bioorganic …, 2023 - Elsevier
Liver cancer has characteristics of high morbidity, high mortality, and poor prognosis.
Metabolic reprogramming is a prominent characteristic of tumors and plays a key role in …
Metabolic reprogramming is a prominent characteristic of tumors and plays a key role in …
Integrated platform of oxygen self-enriched nanovesicles: SP94 peptide-directed chemo/sonodynamic therapy for liver cancer
W Zhang, B Han, C Gao, X Liu, Y Peng, C Gong… - European Journal of …, 2022 - Elsevier
Hepatocellular carcinoma (HCC) is a most common primary liver cancer among the most
deadly malignancies. Selectively killing the cancer cells within the liver urgently requires the …
deadly malignancies. Selectively killing the cancer cells within the liver urgently requires the …
[HTML][HTML] Purine synthesis inhibitor L-alanosine impairs mitochondrial function and stemness of brain tumor initiating cells
Glioblastoma (GBM) is a lethal brain cancer exhibiting high levels of drug resistance, a
feature partially imparted by tumor cell stemness. Recent work shows that homozygous …
feature partially imparted by tumor cell stemness. Recent work shows that homozygous …