Pyrrolopyrimidines: An update on recent advancements in their medicinal attributes

S Pathania, RK Rawal - European Journal of Medicinal Chemistry, 2018 - Elsevier
Fused heterocycles are reported to demonstrate variety of biological activities such as
anticancer, antibacterial, antifungal and anti-inflammatory, and are thus exhaustively utilized …

Piperidine‐Mediated [3+ 2] Cyclization of Donor‐Acceptor Cyclopropanes and β‐Nitrostyrenes: Access to Polysubsituted Cyclopentenes with High Diastereoselectivity

J Xin, C Dai, Y Zhang, C Wang - Asian Journal of Organic …, 2021 - Wiley Online Library
Abstract Piperidine‐mediated [3+ 2] cyclization of cyclopropane‐1, 1‐dicarbonitriles and β‐
nitrostyrenes was developed to generate highly diastereoselective polysubstituted cyclopent …

[图书][B] Exploring chemistry with pyridine derivatives

S Pal - 2023 - books.google.com
This book discusses the chemistry and applications of pyridine derivatives. The library of
pyridine derivatives is growing steadily with numerous synthetic analogues already …

Two new pyrrolo[2,3-d]pyrimidines (7-deazapurines): ultrasonic-assisted synthesis, experimental and theoretical characterizations as well as antibacterial evaluation

S Vazirimehr, A Davoodnia… - … für Naturforschung B, 2017 - degruyter.com
Abstract Two new pyrrolo [2, 3-d] pyrimidines (7-deazapurines) were synthesized in high
yields by the reaction of 2-amino-1-methyl-4, 5-diphenyl-1 H-pyrrole-3-carbonitrile with …

[HTML][HTML] Fused Pyridine Derivatives: Synthesis and Biological Activities

H Istanbullu, G Bayraktar, M Saylam - Exploring Chemistry with …, 2022 - intechopen.com
Five-membered heteroaromatic ring fused pyridine derivatives are of increasing interest in
drug design and medicinal chemistry. The structural similarity of many drugs (especially …

Novel pyrrolo [2, 3-b] pyridine and pyrrolo [2, 3-d] pyrimidine derivatives: Design, synthesis, and structure elucidation

KMH Hilmy, FNM Kishk, EBA Shahen… - Bulletin of the Chemical …, 2023 - ajol.info
A cyclo condensation reaction is an effective method for a two-component reaction of 2-
amino-1, 5-diphenyl-1H-pyrrole-3-carbonitrile 3a-c and active methylene compounds in …

Synthesis of Heterocyclic Compounds Using ketoacids-based Multicomponent Reactions and Evaluation of Their Anti-prion Activities

A HSSKIA, M JASSEM - 2018 - etheses.whiterose.ac.uk
Prion disease is also known as transmissible spongiform encephalopathies (TSEs). They
are incurable and fatal neurodegenerative diseases influencing both humans and animals …