Molecular biomarkers for vascular cognitive impairment and dementia

S Hosoki, GK Hansra, T Jayasena, A Poljak… - Nature Reviews …, 2023 - nature.com
As disease-specific interventions for dementia are being developed, the ability to identify the
underlying pathology and dementia subtypes is increasingly important. Vascular cognitive …

Role of inflammatory markers in the diagnosis of vascular contributions to cognitive impairment and dementia: a systematic review and meta-analysis

C Custodero, A Ciavarella, F Panza, D Gnocchi… - Geroscience, 2022 - Springer
Vascular contribution to cognitive impairment and dementia (VCID) is a clinical label
encompassing a wide range of cognitive disorders progressing from mild to major vascular …

Emerging biomarkers in vascular cognitive impairment and dementia: from pathophysiological pathways to clinical application

V Cipollini, F Troili, F Giubilei - International journal of molecular sciences, 2019 - mdpi.com
Vascular pathology is the second most common neuropathology of dementia after
Alzheimer's disease (AD), with small vessels disease (SVD) being considered the major …

Serum exosomal miR-223 serves as a potential diagnostic and prognostic biomarker for dementia

H Wei, Y Xu, W Xu, Q Zhou, Q Chen, M Yang, F Feng… - Neuroscience, 2018 - Elsevier
The aims of this study were to examine the levels of serum and exosomal miR-137, miR-155
and miR-223, three neuroinflammation-related miRNAs, in dementia patients and to explore …

Cellular mechanisms of fibrin (ogen): insight from neurodegenerative diseases

T Wen, Z Zhang - Frontiers in Neuroscience, 2023 - frontiersin.org
Neurodegenerative diseases are prevalent and currently incurable conditions that
progressively impair cognitive, behavioral, and psychiatric functions of the central or …

Hepatopancreatic metabolic disorders and their implications in the development of Alzheimer's disease and vascular dementia

FI Pinheiro, I Araújo-Filho, ACM do Rego… - Ageing Research …, 2024 - Elsevier
Dementia has been faced with significant public health challenges and economic burdens
that urges the need to develop safe and effective interventions. In recent years, an …

Deep learning based diagnosis of Alzheimer's disease using FDG-PET images

N Kishore, N Goel - Neuroscience Letters, 2023 - Elsevier
Purpose The aim of this study is to develop a deep neural network to diagnosis Alzheimer's
disease and categorize the stages of the disease using FDG-PET scans …

Serum sirtuin-1, HMGB1-TLR4, NF-KB and IL-6 levels in Alzheimer's: the relation between neuroinflammatory pathway and severity of dementia

N Gulmammadli, D Konukoğlu… - Current Alzheimer …, 2022 - ingentaconnect.com
Alzheimer's disease (AD), which affects the world's aging population, is a progressive
neurodegenerative disease requiring markers or tools to accurately and easily diagnose …

[HTML][HTML] Circulating cytokines and vascular dementia: A bi-directional Mendelian randomization study

Y Xia, Z Xu, Y Zhang, D Jiang, Y Zhu, X Liang… - Experimental …, 2024 - Elsevier
Inflammatory responses are associated with the development of vascular dementia (VaD).
Circulating cytokines modulate the inflammatory response and are important for the immune …

Relationship between fibrinogen level and its regulatory gene with alzheimer's disease and vascular dementia

Y Sun, Q Li, W Liu, B Zhang - Journal of International …, 2020 - journals.sagepub.com
Objective Several investigations have shown that the level of fibrinogen (Fg) is associated
with the susceptibility to dementia and is usually affected by polymorphisms in its gene. Our …