Cerebral small vessel disease (cSVD) is a major cause of stroke and dementia. This review
summarizes recent developments in advanced neuroimaging of cSVD with a focus on …

Age-associated cerebral small vessel disease (CSVD) represents a clinically heterogenous
condition, arising from diverse microvascular mechanisms. These lead to chronic …

Abstract The Rotterdam Study is a population-based cohort study, started in 1990 in the
district of Ommoord in the city of Rotterdam, the Netherlands, with the aim to describe the …

Alzheimer's disease and cerebral small vessel disease are the two leading causes of
cognitive decline and dementia and coexist in most memory clinic patients. White matter …

Objective Cerebral small vessel diseases (cSVDs) are a major cause of stroke and
dementia. We used cutting‐edge 7T‐MRI techniques in patients with Cerebral Autosomal …

Cysteine-altering missense variants (NOTCH3 cys) in one of the 34 epidermal growth-factor-
like repeat (EGFr) domains of the NOTCH3 protein are the cause of NOTCH3-associated …

Cerebrovascular disease is a major cause of cognitive decline and dementia. This is
referred to as vascular cognitive impairment (VCI). Diagnosing VCI is important, among …

Background: Hypertension is the leading modifiable risk factor for cerebral small vessel
diseases (SVDs). Yet, it is unknown whether antihypertensive drug classes differentially …

Background Post-stroke cognitive impairment (PSCI) is a common consequence of stroke.
Accurate prediction of PSCI risk is challenging. The recently developed network impact …

In cerebral small vessel disease (cSVD), whole brain MRI markers of cSVD-related brain
injury explain limited variance to support individualized prediction. Here, we investigate …