[HTML][HTML] Polymer-and lipid-based gene delivery technology for CAR T cell therapy
Chimeric antigen receptor T cell (CAR T cell) therapy is a revolutionary approach approved
by the FDA and EMA to treat B cell malignancies and multiple myeloma. The production of …
by the FDA and EMA to treat B cell malignancies and multiple myeloma. The production of …
Thiolated-polymer-based nanoparticles as an avant-garde approach for anticancer therapies—reviewing thiomers from chitosan and hyaluronic acid
R Grosso, MV de-Paz - Pharmaceutics, 2021 - mdpi.com
Thiomers (or thiolated polymers) have broken through as avant-garde approaches in
anticancer therapy. Their distinguished reactivity and properties, closely linked to their final …
anticancer therapy. Their distinguished reactivity and properties, closely linked to their final …
Star Polymer Nanomedicines─ challenges and future perspectives
Star polymers are structures composed of multiple functional linear arms covalently
connected through a central core. The unique conformation of star polymers, with their …
connected through a central core. The unique conformation of star polymers, with their …
Sustained endosomal release of a neurokinin-1 receptor antagonist from nanostars provides long-lasting relief of chronic pain
R Latorre, PD Ramírez-Garcia, A Hegron, JL Grace… - Biomaterials, 2022 - Elsevier
Soft polymer nanoparticles designed to disassemble and release an antagonist of the
neurokinin 1 receptor (NK 1 R) in endosomes provide efficacious yet transient relief from …
neurokinin 1 receptor (NK 1 R) in endosomes provide efficacious yet transient relief from …
Nanoparticle delivery platforms for RNAi therapeutics targeting COVID-19 disease in the respiratory tract
Since December 2019, a pandemic of COVID-19 disease, caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has rapidly spread across the globe. At …
respiratory syndrome coronavirus 2 (SARS-CoV-2), has rapidly spread across the globe. At …
An antibody fragment-decorated liposomal conjugate targets Philadelphia-like acute lymphoblastic leukemia
SMA Mohamed, P Schofield, H McCalmont… - International Journal of …, 2024 - Elsevier
Philadelphia-like acute lymphoblastic leukemia (Ph-like ALL) is an aggressive B-ALL
malignancy associated with high rates of relapse and inferior survival rate. While targeted …
malignancy associated with high rates of relapse and inferior survival rate. While targeted …
Synthesis and Characterization of Ciprofloxacin Loaded Star-Shaped Polycaprolactone–Polyethylene Glycol Hydrogels for Oral Delivery
The administration of poorly water-soluble drugs represents a relevant problem due to the
low body fluids transport efficiency through hydrophilic hydrogels. Star-shaped co-polymers …
low body fluids transport efficiency through hydrophilic hydrogels. Star-shaped co-polymers …
Nitroxide-functional PEGylated nanostars arrest cellular oxidative stress and exhibit preferential accumulation in co-cultured breast cancer cells
The limited application of traditional antioxidants to reducing elevated levels of reactive
oxygen species (ROS) is potentially due to their lack of stability and biocompatibility when …
oxygen species (ROS) is potentially due to their lack of stability and biocompatibility when …
[PDF][PDF] A Comprehensive Review in Novel Therapeutics in Acute Leukemia
A Gholamzad, G Daryoushi, M Khatibi… - IJCMCR 2022; 19 …, 2022 - researchgate.net
In recent years, acute leukemia has become a challenging disease for children, adolescents
and adults, so there are always different treatments; None of them are considered as a …
and adults, so there are always different treatments; None of them are considered as a …
[PDF][PDF] A Comprehensive Review in Novel Therapeutics in Acute Leukemia
P No - ijirme.com
In recent years, acute leukemia has become a challenging disease for children, adolescents
and adults, so there are always different treatments; None of them are considered as a …
and adults, so there are always different treatments; None of them are considered as a …