Effects of SGLT2 inhibitors on stroke and its subtypes in patients with type 2 diabetes: a systematic review and meta-analysis
WH Tsai, SM Chuang, SC Liu, CC Lee, MN Chien… - Scientific reports, 2021 - nature.com
Abstract Sodium-glucose cotransporter 2 (SGLT2) inhibitors have shown impressive effects
in reducing major vascular events in several randomized controlled trials (RCTs). The …
in reducing major vascular events in several randomized controlled trials (RCTs). The …
Do SGLT2 inhibitors and GLP-1 receptor agonists modulate differently the risk of stroke? Discordance between randomised controlled trials and observational studies
AJ Scheen - Diabetes & Metabolism, 2023 - Elsevier
Stroke represents a major burden in patients with type 2 diabetes, yet this cerebrovascular
complication has been less carefully investigated than the risk of cardiovascular mortality …
complication has been less carefully investigated than the risk of cardiovascular mortality …
[HTML][HTML] The role of SGLT2 inhibitors in vascular aging
L Liu, YQ Ni, JK Zhan, YS Liu - Aging and disease, 2021 - ncbi.nlm.nih.gov
Vascular aging is defined as organic and functional changes in blood vessels, in which
decline in autophagy levels, DNA damage, MicroRNA (miRNA), oxidative stress, sirtuin, and …
decline in autophagy levels, DNA damage, MicroRNA (miRNA), oxidative stress, sirtuin, and …
SGLT2 inhibitors and bladder cancer: analysis of cases reported in the European Pharmacovigilance Database
M Garcia, U Arteche‐Martinez… - The Journal of …, 2021 - Wiley Online Library
The association between sodium‐glucose cotransporter 2 inhibitors (SGLT2is) and cancer
risk is unclear. The objective of this study was to analyze whether a disproportionate number …
risk is unclear. The objective of this study was to analyze whether a disproportionate number …
Differential effects of sodium–glucose cotransporter 2 inhibitors on cardiovascular and renal outcomes according to renal function: a dose–response meta-analysis …
DSH Lin, AL Yu, HY Lo, CW Lien, JK Lee… - European Journal of …, 2023 - academic.oup.com
Background The main target of sodium–glucose cotransporter 2 inhibitors (SGLT2i), the
sodium–glucose cotransporters 2, is found in the kidneys, and their activity is reduced in …
sodium–glucose cotransporters 2, is found in the kidneys, and their activity is reduced in …
Polypharmacology of clinical sodium glucose co‐transport protein 2 inhibitors and relationship to suspected adverse drug reactions
K Matharu, K Chana, CJ Ferro… - Pharmacology Research …, 2021 - Wiley Online Library
Sodium glucose co‐transporter 2 inhibitors (SGLT2i) are a promising second‐line treatment
strategy for type 2 diabetes mellitus (T2DM) with a developing landscape of both beneficial …
strategy for type 2 diabetes mellitus (T2DM) with a developing landscape of both beneficial …
Safety of memantine in combination with potentially interactive drugs in the real world: a pharmacovigilance study using the japanese adverse drug event report …
Background: Memantine, an NMDA receptor antagonist, is used for the treatment of
Alzheimer's disease. There is a caution to refrain from administrating memantine in …
Alzheimer's disease. There is a caution to refrain from administrating memantine in …
Stress cardiomyopathy (Takotsubo syndrome) in patients who received adrenergic agonist drugs: A pharmacovigilance study using the Japanese Adverse Drug Event …
Abstract Introduction Stress cardiomyopathy, or Takotsubo syndrome (TTS), is an acute and
reversible syndrome developing in strong association with psychological or physiological …
reversible syndrome developing in strong association with psychological or physiological …
Analysis of Adverse Events of Cholinesterase Inhibitors and NMDA Receptor Antagonists on Arrhythmias Using the Japanese Adverse Drug Event Report Database
S Kobayashi, N Sugama, H Nagano… - Drugs-Real World …, 2023 - Springer
Background The association between anti-dementia drugs and arrhythmia is uncertain. In
addition, the effects of certain drug combinations are not yet well known. Objective We …
addition, the effects of certain drug combinations are not yet well known. Objective We …
Neuroprotective potential of gliflozins
AS Kokin, LA Suplotova - Diabetes mellitus, 2023 - dia-endojournals.ru
Gliflozins are a relatively new class of oral antihyperglycemic drugs that are increasingly
being introduced into routine practice in the treatment of patients with type 2 diabetes …
being introduced into routine practice in the treatment of patients with type 2 diabetes …