Visualizing motions within the cochlea's organ of Corti and illuminating cochlear mechanics with optical coherence tomography
Beginning in 2006, optical coherence tomography (OCT) has been adapted for use as a
vibrometer for hearing research. The application of OCT in this field, particularly for studying …
vibrometer for hearing research. The application of OCT in this field, particularly for studying …
Otoacoustic emissions reveal the micromechanical role of organ-of-Corti cytoarchitecture in cochlear amplification
The intricate, crystalline cytoarchitecture of the mammalian organ of Corti presumably plays
an important role in cochlear amplification. As currently understood, the oblique, Y-shaped …
an important role in cochlear amplification. As currently understood, the oblique, Y-shaped …
Overturning the mechanisms of cochlear amplification via area deformations of the organ of Corti
The mammalian ear embeds a cellular amplifier that boosts sound-induced
hydromechanical waves as they propagate along the cochlea. The operation of this amplifier …
hydromechanical waves as they propagate along the cochlea. The operation of this amplifier …
Reconstruction of transverse-longitudinal vibrations in the organ of Corti complex via optical coherence tomography
BL Frost, CE Strimbu, ES Olson - The Journal of the Acoustical Society …, 2023 - pubs.aip.org
Optical coherence tomography (OCT) is a common modality for measuring vibrations within
the organ of Corti complex (OCC) in vivo. OCT's uniaxial nature leads to limitations that …
the organ of Corti complex (OCC) in vivo. OCT's uniaxial nature leads to limitations that …
Corti fluid is a medium for outer hair cell force transmission
The mammalian cochlea amplifies sounds selectively to improve frequency resolution.
However, vibrations around the outer hair cells (OHCs) are amplified nonselectively. The …
However, vibrations around the outer hair cells (OHCs) are amplified nonselectively. The …
Compressed sensing on displacement signals measured with optical coherence tomography
BL Frost, NP Janjušević, CE Strimbu… - Biomedical Optics …, 2023 - opg.optica.org
Optical coherence tomography (OCT) is capable of angstrom-scale vibrometry of particular
interest to researchers of auditory mechanics. We develop a method for compressed …
interest to researchers of auditory mechanics. We develop a method for compressed …
Asymmetric vibrations in the organ of Corti by outer hair cells measured from excised gerbil cochlea
Pending questions regarding cochlear amplification and tuning are hinged upon the organ
of Corti (OoC) active mechanics: how outer hair cells modulate OoC vibrations. Our …
of Corti (OoC) active mechanics: how outer hair cells modulate OoC vibrations. Our …
Intracochlear overdrive: Characterizing nonlinear wave amplification in the mouse apex
A Altoè, KK Charaziak - The Journal of the Acoustical Society of …, 2023 - pubs.aip.org
In this study, we explore nonlinear cochlear amplification by analyzing basilar membrane
(BM) motion in the mouse apex. Through in vivo, postmortem, and mechanical suppression …
(BM) motion in the mouse apex. Through in vivo, postmortem, and mechanical suppression …
On the tonotopy of the low-frequency region of the cochlea
It is generally assumed that frequency selectivity varies along the cochlea. For example, at
the base of the cochlea, which is a region sensitive to high-frequency sounds, the best …
the base of the cochlea, which is a region sensitive to high-frequency sounds, the best …
Narrow elliptical motion at the outer hair cell-Deiters' cell junction explains disparate features of uniaxial displacement measurements
BL Frost, CE Strimbu, ES Olson - Hearing Research, 2025 - Elsevier
Sound-evoked displacement responses at the outer hair cell-Deiters' cell junction (OHC-DC)
are of significant interest in cochlear mechanics, as OHCs are believed to be in part …
are of significant interest in cochlear mechanics, as OHCs are believed to be in part …