Metabolic reprogramming of colorectal cancer cells and the microenvironment: implication for therapy

M Nenkov, Y Ma, N Gaßler, Y Chen - International journal of molecular …, 2021 - mdpi.com
Colorectal carcinoma (CRC) is one of the most frequently diagnosed carcinomas and one of
the leading causes of cancer-related death worldwide. Metabolic reprogramming, a hallmark …

Chemico-biological aspects of (−)-epigallocatechin-3-gallate (EGCG) to improve its stability, bioavailability and membrane permeability: Current status and future …

R Sahadevan, S Singh, A Binoy… - Critical Reviews in Food …, 2023 - Taylor & Francis
Natural products have been a bedrock for drug discovery for decades.(−)-Epigallocatechin-3-
gallate (EGCG) is one of the widely studied natural polyphenolic compounds derived from …

Nrf2‐interacting nutrients and COVID‐19: time for research to develop adaptation strategies

J Bousquet, JP Cristol, W Czarlewski… - Clinical and …, 2020 - Wiley Online Library
There are large between‐and within‐country variations in COVID‐19 death rates. Some very
low death rate settings such as Eastern Asia, Central Europe, the Balkans and Africa have a …

Role of plant-derived active constituents in cancer treatment and their mechanisms of action

AW Khan, M Farooq, M Haseeb, S Choi - Cells, 2022 - mdpi.com
Despite significant technological advancements in conventional therapies, cancer remains
one of the main causes of death worldwide. Although substantial progress has been made …

Natural polyphenols for treatment of colorectal cancer

Y Zhang, K Liu, C Yan, Y Yin, S He, L Qiu, G Li - Molecules, 2022 - mdpi.com
Colorectal cancer (CRC) is a prevalent and serious gastrointestinal malignancy with high
mortality and morbidity. Chemoprevention refers to a newly emerged strategy that uses …

Immunomodulatory potential of flavonoids for the treatment of autoimmune diseases and tumour

L Han, Q Fu, C Deng, L Luo, T Xiang… - … Journal of Immunology, 2022 - Wiley Online Library
The immune system plays an indispensable role in maintaining human health against the
invasion of foreign materials, microorgainisms and pathogens. The autoimmune diseases …

Polyphenols of the mediterranean diet and their metabolites in the prevention of colorectal cancer

A Yammine, A Namsi, D Vervandier-Fasseur… - Molecules, 2021 - mdpi.com
The Mediterranean diet is a central element of a healthy lifestyle, where polyphenols play a
key role due to their anti-oxidant properties, and for some of them, as nutripharmacological …

[HTML][HTML] Innovative strategies to Combat 5-fluorouracil resistance in colorectal cancer: The role of phytochemicals and extracellular vesicles

M Barathan, AK Zulpa, SL Ng, Y Lokanathan… - International Journal of …, 2024 - mdpi.com
Colorectal cancer (CRC) is a significant public health challenge, with 5-fluorouracil (5-FU)
resistance being a major obstacle to effective treatment. Despite advancements, resistance …

Resveratrol, epigallocatechin gallate and curcumin for cancer therapy: challenges from their pro-apoptotic properties

A Chimento, M D'Amico, A De Luca, FL Conforti… - Life, 2023 - mdpi.com
Plant-derived bioactive compounds are gaining wide attention for their multiple health-
promoting activities and in particular for their anti-cancer properties. Several studies have …

[HTML][HTML] Phytochemistry and anticancer therapeutics of Camellia sinensis (Green tea)

N Singh, P Sahjlan, SS Yadav - Pharmacological Research-Modern …, 2024 - Elsevier
Introduction Tea is one of the most consumed beverages after water. It is obtained from the
leaves of Camellia sinensis. Based on processing, it is classified as green, black, white …