RNA modifications have become hot topics recently. By influencing RNA processes,
including generation, transportation, function, and metabolization, they act as critical …

RNAs fold into 3D structures that range from simple helical elements to complex tertiary
structures and quaternary ribonucleoprotein assemblies. The functions of many regulatory …

The recent discovery of reversible mRNA methylation has opened a new realm of post-
transcriptional gene regulation in eukaryotes. The identification and functional …

RNA modifications are important regulatory elements of RNA functions. However, most
genome-wide mapping of RNA modifications has focused on messenger RNAs and transfer …

Studies on biological functions of RNA modifications such as N 6-methyladenosine (m6A) in
mRNA have sprung up in recent years, while the roles of N 1-methyladenosine (m1A) in …

ABSTRACT RNA modifications have long been known to be central in the proper function of
tRNA and rRNA. While chemical modifications in mRNA were discovered decades ago, their …

Post-transcriptional modifications in RNAs regulate their biological behaviors and functions.
N 1-methyladenosine (m 1 A), which is dynamically regulated by writers, erasers and …

A growing number of nucleobase modifications in messenger RNA have been revealed
through advances in detection and RNA sequencing. Although some of the biochemical …

Nucleic acid modifications in DNA and RNA ubiquitously exist among all the three kingdoms
of life. This trait significantly broadens the genome diversity and works as an important …

The 5′ and 3′ untranslated regions (UTRs) regulate crucial aspects of post-transcriptional
gene regulation that are necessary for the maintenance of cellular homeostasis. When these …