Acute fluid biomarkers for diagnosis and prognosis in children with mild traumatic brain injury: A systematic review

AK Malhotra, K Ide, Z Salaheen, Q Mahood… - Molecular Diagnosis & …, 2024 - Springer
Abstract Background and Objective Fluid biomarkers have the potential to improve the
accuracy of diagnosis and prognosis in children with mild traumatic brain injury. Our primary …

Targeting brain-peripheral immune responses for secondary brain injury after ischemic and hemorrhagic stroke

M Duan, Y Xu, Y Li, H Feng, Y Chen - Journal of Neuroinflammation, 2024 - Springer
The notion that the central nervous system is an immunologically immune-exempt organ has
changed over the past two decades, with increasing evidence of strong links and …

High Neutrophil-to-Lymphocyte Ratio Facilitates Cancer Growth—Currently Marketed Drugs Tadalafil, Isotretinoin, Colchicine, and Omega-3 to Reduce It: The TICO …

RE Kast - Cancers, 2022 - mdpi.com
Simple Summary Several elements that are composed of, or related to, neutrophils, have
been shown to inhibit strong immune responses to cancer and promote cancers' growth …

Performance of the neutrophil–lymphocyte ratio as a predictor of severity and mortality in children and adolescents with traumatic brain injury

JRT Melo, MHH Masini, JG de Oliveira… - Child's Nervous System, 2024 - Springer
Purpose An inflammatory cascade associated with the systemic neutrophil response can be
triggered after traumatic brain injury (TBI), causing neuronal dysfunction, which is …

[PDF][PDF] Is neutrophil-to-lymphocyte ratio a prognostic marker for traumatic brain injury in the pediatric population?

HS Cine, E Uysal, MS Gurbuz - European Review for Medical & …, 2023 - europeanreview.org
OBJECTIVE: The neutrophil-tolymphocyte ratio (NLR) is used for the prognosis of diseases
characterized by inflammatory processes. This study aims to discuss the longterm outcomes …

[HTML][HTML] Blood biomarkers for prediction of positive CT findings in mild traumatic brain injury in paediatric population

T Siempis, PA Georgalis, G Lianos… - Journal of Integrative …, 2023 - imrpress.com
Background: Paediatric Traumatic Brain Injury (TBI) has received less research attention
compared to TBI in adults, despite its potential morbidity in all ages. Our aim was to …

Neutrophil to lymphocyte ratio as a predictor of postoperative outcomes in traumatic brain injury: a systematic review and meta-analysis

A Nguyen, A Nguyen, TI Hsu, HD Lew, N Gupta… - Diseases, 2023 - mdpi.com
(1) Introduction: Traumatic brain injury (TBI) is a leading cause of injury and mortality
worldwide, carrying an estimated cost of $38 billion in the United States alone. Neutrophil to …

[HTML][HTML] Utility of systemic immune-inflammation index, neutrophil-to-lymphocyte ratio, and platelet-to-lymphocyte ratio as a predictive biomarker in pediatric traumatic …

MA Parenrengi, W Suryaningtyas… - Surgical Neurology …, 2024 - pmc.ncbi.nlm.nih.gov
Background: Traumatic brain injury (TBI) remains the predominant cause of mortality and
disability among the pediatric population. At present, there are no radiation-free, simple, and …

The Neuroimmune Interface: Age-Related Responses to Traumatic Brain Injury

J Leonard, L Ladner, EA Harris, C de Jager… - Traumatic Brain Injuries …, 2024 - Springer
Abstract Traumatic Brain Injury (TBI) is a significant public health issue, with diverse
consequences across the lifespan. This comprehensive review explores the complex …

[PDF][PDF] Prognostıc and diagnostic importance of the systemic immune-inflammation index in pediatric head trauma

K Sener, A Cakir, HI Toksul, H Olmez, MO Tugcan… - Medicine, 2023 - researchgate.net
Head trauma is a leading cause of mortality and morbidity in pediatric patients. The trauma
itself leads to the activation of a biomolecular cascade of damage. Purinergic receptors and …