Recent advances in Bio-conjugated nanocarriers for crossing the Blood-Brain Barrier in (pre-) clinical studies with an emphasis on vesicles

A Poustforoosh, MH Nematollahi… - Journal of Controlled …, 2022 - Elsevier
The brain is one of the most challenging organs for drug delivery. It is preserved by the
blood-brain barrier (BBB), which controls the transport of components into and out of the …

Nanovaccines against animal pathogens: The latest findings

CT Celis-Giraldo, J López-Abán, A Muro, MA Patarroyo… - Vaccines, 2021 - mdpi.com
Nowadays, safe and efficacious vaccines represent powerful and cost-effective tools for
global health and economic growth. In the veterinary field, these are undoubtedly key tools …

The impact of D614G mutation of SARS-COV-2 on the efficacy of anti-viral drugs: A comparative molecular docking and molecular dynamics study

A Poustforoosh, H Hashemipour, B Tüzün… - Current …, 2022 - Springer
D614G is one of the most reported mutations in the spike protein of SARS-COV-2 that has
altered some crucial characteristics of coronaviruses, such as rate of infection and binding …

In silico SELEX screening and statistical analysis of newly designed 5mer peptide-aptamers as Bcl-xl inhibitors using the Taguchi method

A Poustforoosh, S Faramarz, MH Nematollahi… - Computers in Biology …, 2022 - Elsevier
Drug development for cancer treatment is a complex process that requires special efforts.
Targeting crucial proteins is the most essential purpose of drug design in cancers. Bcl-xl is …

Construction of Bio-conjugated nano-vesicles using non-ionic surfactants for targeted drug delivery: A computational supported experimental study

A Poustforoosh, S Farmarz, MH Nematollahi… - Journal of Molecular …, 2022 - Elsevier
Introduction Targeted delivery of drugs to the brain is a complicated activity. This
complication is caused by the blood–brain barrier (BBB). Interestingly, there are various …

Investigation on the mechanisms by which the herbal remedies induce anti-prostate cancer activity: uncovering the most practical natural compound

A Poustforoosh, S Faramarz… - Journal of …, 2024 - Taylor & Francis
Prostate cancer (PCa) is one of the most reported cancers among men worldwide. Targeting
the essential proteins associated with PCa could be a promising method for cancer …

Synthesis and biological activity of functionally substituted pyrimidine and pyran derivatives on the basis of isatylidene malononitriles

F Naghiyev, I Mamedov, R Askerov, P Taslimi… - …, 2022 - Wiley Online Library
In this study, it was shown that pyrimidine and imidazopyridine derivatives were obtained
from the multicomponent reaction of isatylidene malononitriles with malononitrile and …

Nanoliposomal formulation of pistachio hull extract: preparation, characterization and anti-cancer evaluation through Bax/Bcl2 modulation

H Harandi, SK Falahati-Pour, M Mahmoodi… - Molecular biology …, 2022 - Springer
Background Pistachio is one of the main crops in Iran. Pistachio green hull, as a by-product
of this fruit, is obtained in large quantities after the processing of pistachios. This novel work …

Carbon Quantum Dots as Multi‐Purpose Nanomaterial in Stem Cell Therapy

K Bahrampour Juybari, K Rizwan… - Chemistry & …, 2023 - Wiley Online Library
During stem cell therapy, some issues, such as obscure fate of stem cells or their low
survival rate in the body, should be addressed to boost their therapeutic efficiency …

A comprehensive and updated review on the applications of vesicular drug delivery systems in treatment of brain disorders: A shelter against storms

MA Rajizadeh, S Motamedy, Y Mir… - Journal of Drug Delivery …, 2023 - Elsevier
Vesicular drug delivery carriers, a subgroup of colloidal drug delivery systems (CDDS), can
be defined as highly ordered assemblies consisting of one or more concentric bilayers …