Cardiovascular disease, including atherosclerosis and atherosclerosis-associated
complications, is an increasing cause of morbidity and mortality in human immunodeficiency …

Cathepsins are mechanosensitive proteases that are regulated not only by biochemical
factors, but are also responsive to biomechanical forces in the cardiovascular system that …

Background HIV patients on highly-active antiretroviral therapy (HAART) have shown
elevated incidence of dyslipidemia, lipodystrophy, and markers of cardiovascular disease …

Endothelial cell activation, injury, and dysfunction underlies the pathophysiology of vascular
diseases and infections associated with vascular dysfunction, including human …

Biaxial testing of blood vessels is the preferred method for biomechanical testing because of
its ability to provide a measure of the anisotropy of these tissues. Small-caliber vessels are …

Mortality from cardiovascular disease (CVD) is predicted to surpass that of infectious
disease in sub-Saharan Africa (SSA) by 2030. HIV doubles the risk of CVD in high resource …

Introducción: El tratamiento antirretroviral, ha aumentado la esperanza de vida en pacientes
VIH, observándose enfermedades asociadas a alteraciones arterioescleróticas, con …

Combination antiretroviral therapy (cART)-treated people living with human
immunodeficiency virus (HIV)(PLWH) face an increased risk of atherosclerosis associated …

Cysteine cathepsins are powerful proteases that can degrade other proteins, among which
are the extracellular matrix proteins collagen and elastin. Multiplex cathepsin zymography is …