Alcohols as Substrates in Transition-Metal-Catalyzed Arylation, Alkylation, and Related Reactions

A Cook, SG Newman - Chemical Reviews, 2024 - ACS Publications
Alcohols are abundant and attractive feedstock molecules for organic synthesis. Many
methods for their functionalization require them to first be converted into a more activated …

Recent Advancements in Typical Friedel–Crafts Alkylation Reactions Focused on Targeting Arene Nucleophiles

S Singh, CK Hazra - Synthesis, 2023 - thieme-connect.com
This review delves into recent advances and significant breakthroughs in the field of the
catalytic Friedel–Crafts alkylation of targeted arenes or heteroarenes. Though a few earlier …

Ruthenium‐Catalyzed Selective α‐Alkylation of β‐Naphthols using Primary Alcohols: Elucidating the Influence of Base and Water

R Vijaya Sankar, A Mathew, S Pradhan… - … A European Journal, 2023 - Wiley Online Library
Functionalized arenes and arenols have diverse applications in chemical synthesis and
material chemistry. Selective functionalization of arenols is a topic of prime interest. In …

HFIP-promoted para-selective alkylation of anilines and phenols with tertiary alkyl bromides

P Huang, X Jiang, D Gao, C Wang, DQ Shi… - Organic Chemistry …, 2023 - pubs.rsc.org
A hexafluoroisopropanol-promoted highly regioselective Friedel–Crafts alkylation of arenes
has been developed in this study. Various arenes, including anilides, anisoles, and phenols …

A Fenton Approach to Aromatic Radical Cations and Diarylmethane Synthesis

RC Iii, B Lujan, A Martinez, R Manasi… - The Journal of …, 2023 - ACS Publications
Manipulating carbon-centered radicals to add to electron-deficient systems is a well-
precedented process. By coupling the Fe (II)-mediated Fenton reaction with the Fe (III) …

Dehydrative Alkylation of Phenols with Alcohols via Formation of Triflate

S Ni, F Zhou, W Zhang, J Ma - The Journal of Organic Chemistry, 2024 - ACS Publications
An efficient synergistic trityl cation ([Ph3C][B (C6F5) 4])/triflic anhydride (Tf2O) catalyzed
alkylation of phenols with alcohols is reported. Benefiting from the formation of the triflate in …

Ruthenium catalyzed dehydrogenative α-C–H functionalization of β-naphthol using alcohols: a metal–ligand cooperative borrowing hydrogen approach

AK Guin, S Chakraborty, S Khanra… - Catalysis Science & …, 2024 - pubs.rsc.org
Chemoselective α-C–H functionalization of β-naphthol is achieved with inexpensive and
readily available alcohols using a well-defined, air-stable, and easy-to-prepare Ru (II) …

Efficient Synthesis of Quinolines from 2‐Aminoaryl Ketones with α‐Methylene Carbonyl Derivatives: Exploiting the Dual Acid Sites of Metal Organic Framework …

B Krishna, S Roy - ChemistrySelect, 2023 - Wiley Online Library
We report on the use of heterogeneous metal organic framework (MOF) catalysts for the
Friedländer synthesis of 2‐aminoaryl ketone with α‐methylene carbonyl derivatives, a …

Iminonaphthofuranone synthesis via multiple-component cyclization of 2-naphthols using only molecular oxygen

J Dong, S Wu, L Liu, D Zhou, M Mo, Y Gao… - Organic Chemistry …, 2025 - pubs.rsc.org
A multiple-component oxidative cyclization of easily available 2-naphthols, anilines, and
ethyl glyoxylate is successfully achieved using only molecular oxygen. The reaction enables …

Titanocene dichloride-catalyzed synthesis of heterocycles accelerated by in-situ formed Lewis and Brønsted acids

YX Yao, L Tu, X Wang, Y Wu, YJ Jian, HM Sun… - Molecular …, 2025 - Elsevier
Titanocene dichloride-catalyzed reaction of aniline derivatives with trialkyl orthoformates/
aldehydes has been developed, enabling the synthesis of 59 N-heterocyclic compounds …