A Rutsch, JB Kantsjö, F Ronchi - Frontiers in immunology, 2020 - frontiersin.org
The human microbiota has a fundamental role in host physiology and pathology. Gut microbial alteration, also known as dysbiosis, is a condition associated not only with …
IL-17 cytokine family members have diverse biological functions, promoting protective immunity against many pathogens but also driving inflammatory pathology during infection …
A Fara, Z Mitrev, RA Rosalia, BM Assas - Open biology, 2020 - royalsocietypublishing.org
Coronavirus disease 2019 (COVID-19) has swept the world, unlike any other pandemic in the last 50 years. Our understanding of the disease has evolved rapidly since the outbreak; …
S Voet, S Srinivasan, M Lamkanfi… - EMBO molecular …, 2019 - embopress.org
Neuroinflammation and neurodegeneration often result from the aberrant deposition of aggregated host proteins, including amyloid‐β, α‐synuclein, and prions, that can activate …
Forty years after its naming, interleukin-1 (IL-1) is experiencing a renaissance brought on by the growing understanding of its context-dependent roles and advances in the clinic. Recent …
CA Dinarello - Immunological reviews, 2018 - Wiley Online Library
Summary The interleukin‐1 (IL‐1) family of cytokines and receptors is unique in immunology because the IL‐1 family and Toll‐like receptor (TLR) families share similar functions. More …
K Yasuda, Y Takeuchi, K Hirota - Seminars in immunopathology, 2019 - Springer
Abstract IL-17-producing T helper (Th17) cells have been implicated in the pathogenesis of many inflammatory and autoimmune diseases. Targeting the effector cytokines IL-17 and …
MG Netea, F Balkwill, M Chonchol, F Cominelli… - Nature …, 2017 - nature.com
Biologists, physicians and immunologists have contributed to the understanding of the cellular participants and biological pathways involved in inflammation. Here, we provide a …
EH Kobayashi, T Suzuki, R Funayama… - Nature …, 2016 - nature.com
Abstract Nrf2 (NF-E2-related factor-2) transcription factor regulates oxidative/xenobiotic stress response and also represses inflammation. However, the mechanisms how Nrf2 …