Reactions in water involving the “On‐Water” mechanism

T Kitanosono, S Kobayashi - Chemistry–A European Journal, 2020 - Wiley Online Library
Ever‐evolving catalyst advances in synthetic protocols using water as a reaction medium
have enriched the understanding of sustainable organic chemistry. Because conventional …

The direct catalytic asymmetric aldol reaction

BM Trost, CS Brindle - Chemical Society Reviews, 2010 - pubs.rsc.org
Asymmetric aldol reactions are a powerful method for the construction of carbon–carbon
bonds in an enantioselective fashion. Historically this reaction has been performed in a …

Kinetic profiling of catalytic organic reactions as a mechanistic tool

DG Blackmond - Journal of the American Chemical Society, 2015 - ACS Publications
The use of modern kinetic tools to obtain virtually continuous reaction progress data over the
course of a catalytic reaction opens up a vista that provides mechanistic insights into both …

Quantum mechanical investigations of organocatalysis: mechanisms, reactivities, and selectivities

PHY Cheong, CY Legault, JM Um… - Chemical …, 2011 - ACS Publications
Organocatalysis has captured the imagination of a significant group of synthetic chemists.
Much of the mechanistic understanding of these reactions has come from computational …

Asymmetric aminocatalysis—gold rush in organic chemistry

P Melchiorre, M Marigo, A Carlone… - Angewandte Chemie …, 2008 - Wiley Online Library
Catalysis with chiral secondary amines (asymmetric aminocatalysis) has become a well‐
established and powerful synthetic tool for the chemo‐and enantioselective functionalization …

Proline and its derivatives as organocatalysts for multi‐component reactions in aqueous media: synergic pathways to the green synthesis of heterocycles

BS Vachan, M Karuppasamy, P Vinoth… - Advanced Synthesis …, 2020 - Wiley Online Library
Proline is a non‐toxic and inexpensive natural amino acid that is readily available in both
enantiomeric forms and was one of the very first compounds to be studied as an …

Mechanisms in aminocatalysis

M Nielsen, D Worgull, T Zweifel, B Gschwend… - Chemical …, 2011 - pubs.rsc.org
Mechanisms in aminocatalysis - Chemical Communications (RSC Publishing) DOI:10.1039/C0CC02417A
Royal Society of Chemistry View PDF VersionPrevious ArticleNext Article DOI: 10.1039/C0CC02417A …

Integration of metal catalysis and organocatalysis in a metal nanocluster with anchored proline

JQ Wang, RL He, WD Liu, QY Feng… - Journal of the …, 2023 - ACS Publications
Chiral metal nanoclusters have recently been attracting great attention. It is challenging to
realize asymmetric catalysis via atomically precise metal nanoclusters. Herein, we report the …

Proline functionalized UiO-67 and UiO-68 type metal–organic frameworks showing reversed diastereoselectivity in aldol addition reactions

C Kutzscher, G Nickerl, I Senkovska, V Bon… - Chemistry of …, 2016 - ACS Publications
Functionalization of dicarboxylate linkers with proline was used to generate catalytically
active metal–organic frameworks (MOFs) for diastereoselective aldol addition. Due to high …

L-Proline: an efficient catalyst for the one-pot synthesis of 2, 4, 5-trisubstituted and 1, 2, 4, 5-tetrasubstituted imidazoles

S Samai, GC Nandi, P Singh, MS Singh - Tetrahedron, 2009 - Elsevier
A simple highly versatile and efficient synthesis of 2, 4, 5-trisubstituted imidazoles is
achieved by three-component cyclocondensation of 1, 2-dicarbonyl compound, aldehyde …