Genetic variation and function of the HIV-1 Tat protein
Human immunodeficiency virus type 1 (HIV-1) encodes a transactivator of transcription (Tat)
protein, which has several functions that promote viral replication, pathogenesis, and …
protein, which has several functions that promote viral replication, pathogenesis, and …
PA-X: a key regulator of influenza A virus pathogenicity and host immune responses
J Hu, C Ma, X Liu - Medical microbiology and immunology, 2018 - Springer
PA-X, a fusion protein belonging to influenza A viruses (IAVs), integrating the N-terminal 191
amino acids of PA gene and the ribosomal frame-shifting product that lengthens out to 41 or …
amino acids of PA gene and the ribosomal frame-shifting product that lengthens out to 41 or …
Induction of IL-17 and nonclassical T-cell activation by HIV-Tat protein
Chronic immune activation is a major complication of antiretroviral therapy (ART) for HIV
infection and can cause a devastating immune reconstitution inflammatory syndrome (IRIS) …
infection and can cause a devastating immune reconstitution inflammatory syndrome (IRIS) …
Elucidating the in vivo interactome of HIV-1 RNA by hybridization capture and mass spectrometry
HIV-1 replication requires myriad interactions between cellular proteins and the viral
unspliced RNA. These interactions are important in archetypal RNA processes such as …
unspliced RNA. These interactions are important in archetypal RNA processes such as …
Protein lysine acetylation and its role in different human pathologies: a proteomic approach
O Morales-Tarré, R Alonso-Bastida… - Expert review of …, 2021 - Taylor & Francis
Introduction Lysine acetylation is a reversible post-translational modification (PTM)
regulated through the action of specific types of enzymes: lysine acetyltransferases (KATs) …
regulated through the action of specific types of enzymes: lysine acetyltransferases (KATs) …
Nucleophosmin: A Nucleolar Phosphoprotein Orchestrating Cellular Stress Responses
MS Taha, MR Ahmadian - Cells, 2024 - pmc.ncbi.nlm.nih.gov
Nucleophosmin (NPM1) is a key nucleolar protein released from the nucleolus in response
to stress stimuli. NPM1 functions as a stress regulator with nucleic acid and protein …
to stress stimuli. NPM1 functions as a stress regulator with nucleic acid and protein …
G-quadruplex DNA recognition by nucleophosmin: new insights from protein dissection
PL Scognamiglio, C Di Natale, M Leone… - … et Biophysica Acta (BBA …, 2014 - Elsevier
Abstract Background Nucleophosmin (NPM1, B23) is a multifunctional protein that is
involved in a variety of fundamental biological processes. NPM1/B23 deregulation is …
involved in a variety of fundamental biological processes. NPM1/B23 deregulation is …
Regulation of host gene expression by HIV-1 TAR microRNAs
DL Ouellet, J Vigneault-Edwards, K Létourneau… - Retrovirology, 2013 - Springer
Background The transactivating response (TAR) element of human immunodeficiency virus
type 1 (HIV-1) is the source of two functional microRNAs (miRNAs), miR-TAR-5p and miR …
type 1 (HIV-1) is the source of two functional microRNAs (miRNAs), miR-TAR-5p and miR …
The presence of HIV-1 Tat protein second exon delays fas protein-mediated apoptosis in CD4+ T lymphocytes: a potential mechanism for persistent viral production
MR Lopez-Huertas, E Mateos, MS Del Cojo… - Journal of Biological …, 2013 - ASBMB
HIV-1 replication is efficiently controlled by the regulator protein Tat (101 amino acids) and
codified by two exons, although the first exon (1–72 amino acids) is sufficient for this …
codified by two exons, although the first exon (1–72 amino acids) is sufficient for this …
Molecular basis for RASSF10/NPM/RNF2 feedback cascade–mediated regulation of gastric cancer cell proliferation
NPL Ch, A Sivagnanam, S Raja… - Journal of Biological …, 2021 - ASBMB
Ras-association domain family (RASSF) proteins are encoded by numerous tumor
suppressor genes that frequently become silenced in human cancers. RASSF10 is …
suppressor genes that frequently become silenced in human cancers. RASSF10 is …