Objective: This article reviews the published studies dealing with the influence of cigarette
smoking on metabolic changes and effectiveness of drugs used in the systemic …

Methods A comprehensive search of related articles was performed focused on phases Ⅱ
and Ⅲ clinical trials studies. Results The lung cancer management should take into …

Background We evaluated the safety and efficacy of induction chemotherapy with
bevacizumab followed by maintenance chemotherapy with bevacizumab for advanced non …

Purpose For patients with advanced nonsquamous non‐small cell lung cancer (NSCLC),
immunotherapy or antiangiogenic therapy combined with pemetrexed and …

Atherosclerotic neovascularization plays a significant role in plaque instability as it provides
additional lipids and inflammatory mediators to lesions, and resulting in intraplaque …

Background Perioperative treatment of locally advanced non-small cell lung cancer
(NSCLC) is attracting attention. The effect of neoadjuvant tyrosine kinase inhibitor (TKI) …

Background: Lung cancer (LC) development is a process that depends on genetic
mutations. The DNA methylation, an important epigenetic modification, is associated with the …

Background: Although oncogene-targeted therapy is a first-line treatment for advanced,
unresectable lung adenocarcinoma harboring a target gene mutation, its effect on potentially …

Lung tumors display intratumoral heterogeneity and contain “cancer stem-like cells”(CS-
LCs) that drive chemoresistance and tumor relapse. Cancer relapse occurs when treatment …

Background This study evaluated the efficacy and safety of switch maintenance erlotinib and
bevacizumab after induction therapy with carboplatin/pemetrexed/bevacizumab for non …