Pluripotent embryonic stem cells (ESC s) are characterized by distinct epigenetic features
including a relative enrichment of histone modifications related to active chromatin. Among …

Prostate cancer is the most commonly diagnosed male malignancy. Despite compelling
epidemiology, there are no definitive aetiological clues linking development to frequency …

Uveal melanoma is an aggressive cancer which has a high percentage recurrence and with
a worse prognosis. Identify the potential prognostic markers of uveal melanoma may provide …

Simple Summary Tumor heterogeneity promotes the development of drug resistance in
cancer. HDAC inhibitors modulate several processes that contribute to intra-tumoral …

Epstein-Barr virus (EBV) infection is associated with a variety of malignancies including
Burkitt's lymphoma (BL), Hodgkin's disease, T cell lymphoma, nasopharyngeal carcinoma …

Glioblastoma (GBM) is the most aggressive and invasive primary brain tumor. Current
therapies are not curative, and patients' outcomes remain poor with an overall survival of …

The onset and progression of breast cancer are linked to genetic and epigenetic changes
that alter the normal programming of cells. Epigenetic modifications of DNA and histones …

Glioblastoma (GBM) is the most common and lethal primary brain malignancy and is
characterized by a high degree of intra and intertumor cellular heterogeneity, a starkly …

Psoriasis is characterized by keratinocyte hyperproliferation. While significant progress has
been made in understanding the molecular mechanism regulating the proliferation of …

Simple Summary A substantial disparity in breast cancer incidence and mortality exists
between African American (AA) and European American (EA) women. However, the basis …