Toripalimab combined with lenvatinib and GEMOX is a promising regimen as first-line treatment for advanced intrahepatic cholangiocarcinoma: a single-center, single …
GM Shi, XY Huang, D Wu, HC Sun, F Liang… - Signal transduction and …, 2023 - nature.com
Advanced intrahepatic cholangiocarcinoma (ICC) has a dismal prognosis. Here, we report
the efficacy and safety of combining toripalimab, lenvatinib, and gemcitabine plus oxaliplatin …
the efficacy and safety of combining toripalimab, lenvatinib, and gemcitabine plus oxaliplatin …
Production of pyrimidine nucleosides in microbial systems via metabolic engineering: Theoretical analysis research and prospects
X Zhang, P Niu, H Liu, H Fang - Biotechnology Advances, 2024 - Elsevier
Pyrimidine nucleosides, as intermediate materials of significant commercial value, find
extensive applications in the pharmaceutical industry. However, the current production of …
extensive applications in the pharmaceutical industry. However, the current production of …
Recent advances in immunotherapy for advanced biliary tract cancer
S Yue, Y Zhang, W Zhang - Current Treatment Options in Oncology, 2024 - Springer
Opinion Statement Biliary tract cancer (BTC) is a heterogeneous group of aggressive
malignancies that arise from the epithelium of the biliary tract. Most patients present with …
malignancies that arise from the epithelium of the biliary tract. Most patients present with …
Circ-RAPGEF5 promotes intrahepatic cholangiocarcinoma progression by stabilizing SAE1 to facilitate SUMOylation
J Zheng, Y Wang, L Tao, J Cai, Z Shen, Y Liu… - Journal of Experimental …, 2023 - Springer
Background Intrahepatic cholangiocarcinoma (ICC) is an aggressive malignancy with a poor
prognosis. The underlying functions and mechanisms of circular RNA and SUMOylation in …
prognosis. The underlying functions and mechanisms of circular RNA and SUMOylation in …
Elucidating the causal association between gut microbiota and intrahepatic cholangiocarcinoma through Mendelian randomization analysis
Z Chen, W Shi, K Chen, C Lu, X Li, Q Li - Frontiers in Microbiology, 2023 - frontiersin.org
Background Intrahepatic cholangiocarcinoma (ICC) is an aggressive liver cancer with poor
prognosis. The gut microbiota has been linked to ICC, but evidence for causality is lacking …
prognosis. The gut microbiota has been linked to ICC, but evidence for causality is lacking …
Impact of sarcopenia on postoperative outcomes after hepatectomy in older patients with intrahepatic cholangiocarcinoma: A multicentre cohort study
Z Zhao, Z Bo, N Ye, Y Dong, Y Xu, B Wang… - Liver …, 2024 - Wiley Online Library
Abstract Background and Aims Sarcopenia is associated with poor prognosis, but its role in
older patients with intrahepatic cholangiocarcinoma (ICC) is unclear. We aimed to evaluate …
older patients with intrahepatic cholangiocarcinoma (ICC) is unclear. We aimed to evaluate …
Overexpression of TBX3 suppresses tumorigenesis in experimental and human cholangiocarcinoma
TBX3 behaves as a tumor suppressor or oncoprotein across cancer. However, TBX3
function remains undetermined in intrahepatic cholangiocarcinoma (iCCA), a deadly primary …
function remains undetermined in intrahepatic cholangiocarcinoma (iCCA), a deadly primary …
Mining the interpretable prognostic features from pathological image of intrahepatic cholangiocarcinoma using multi-modal deep learning
GY Ding, WM Tan, YP Lin, Y Ling, W Huang, S Zhang… - BMC medicine, 2024 - Springer
Background The advances in deep learning-based pathological image analysis have
invoked tremendous insights into cancer prognostication. Still, lack of interpretability remains …
invoked tremendous insights into cancer prognostication. Still, lack of interpretability remains …
Differentiation of hepatocellular carcinoma from intrahepatic cholangiocarcinoma through MRI radiomics
N Liu, Y Wu, Y Tao, J Zheng, X Huang, L Yang… - Cancers, 2023 - mdpi.com
Simple Summary The noninvasive differentiation of hepatocellular carcinoma (HCC) from
intrahepatic cholangiocarcinoma (ICC) remains challenging. In recent years, the number of …
intrahepatic cholangiocarcinoma (ICC) remains challenging. In recent years, the number of …
[HTML][HTML] Predicting very early recurrence in intrahepatic cholangiocarcinoma after curative hepatectomy using machine learning radiomics based on CECT: A multi …
B Chen, Y Mao, J Li, Z Zhao, Q Chen, Y Yu… - Computers in Biology …, 2023 - Elsevier
Background Even after curative resection, the prognosis for patients with intrahepatic
cholangiocarcinoma (iCCA) remains disappointing due to the extremely high incidence of …
cholangiocarcinoma (iCCA) remains disappointing due to the extremely high incidence of …