Graphics are widely used to provide summarization of complex data in scientific
publications. Although there are many tools available for drawing graphics, their use is …

The tumor microenvironment (TME) is a unique niche governed by constant crosstalk within
and across all intratumoral cellular compartments. In particular, intratumoral high potassium …

Thyroid hormones are essential for proper kidney growth and development. The kidney is
not only the organ of thyroid hormone metabolism but also the target organ of thyroid …

Preterm infants with oxygen supplementation are at high risk for bronchopulmonary
dysplasia (BPD), a neonatal chronic lung disease. Inflammation with macrophage activation …

Inflammation is a physiological condition characterized by a complex interplay between
different cells handled by metabolites and specific inflammatory-related molecules. In some …

In living systems, potassium ion (K+) plays a vital role in a variety of physiological functions,
whose dyshomeostasis has been seen as a biomarker of many diseases. Consequently …

Background Sepsis is a systemic inflammatory syndrome that can lead to multiple organ
dysfunction and life-threatening complications. Sepsis-induced myocardial dysfunction …

The adaptive T cell response is accompanied by continuous rewiring of the T cell's electric
and metabolic state. Ion channels and nutrient transporters integrate bioelectric and …

Diverse ion channels have dysregulated functional expression in the tumor
microenvironment (TME). In this issue of Cell Metabolism, Chen et al. reveal that high …

Neuroinflammation is highly influenced by microglia, particularly through activation of the
NLRP3 inflammasome and subsequent release of IL-1β. Extracellular ATP is a strong …