Lymphocyte function during hepatic ischemia/reperfusion injury

CC Caldwell, J Tschoep… - Journal of Leucocyte …, 2007 - academic.oup.com
The liver is the primary organ affected by ischemia/reperfusion (I/R) injury after shock,
surgical resection, or transplantation. The actions of myeloid leukocytes have been well …

Regulation of B‐cell entry into the cell cycle

S Richards, C Watanabe, L Santos… - Immunological …, 2008 - Wiley Online Library
B cells are induced to enter the cell cycle by stimuli including ligation of the B‐cell receptor
(BCR) complex and Toll‐like receptor (TLR) agonists. This review discusses the contribution …

An early Ca2+ influx is a prerequisite to thaxtomin A-induced cell death in Arabidopsis thaliana cells

R Errakhi, A Dauphin, P Meimoun… - Journal of …, 2008 - academic.oup.com
The pathogenicity of various Streptomyces scabies isolates involved in potato scab disease
was correlated with the production of thaxtomin A. Since calcium is known as an essential …

Deciphering early events involved in hyperosmotic stress-induced programmed cell death in tobacco BY-2 cells

E Monetti, T Kadono, D Tran, E Azzarello… - Journal of …, 2014 - academic.oup.com
Hyperosmotic stresses represent one of the major constraints that adversely affect plants
growth, development, and productivity. In this study, the focus was on early responses to …

[HTML][HTML] Loss of the protein tyrosine phosphatase PTPN22 reduces mannan-induced autoimmune arthritis in SKG mice

S Sood, RJ Brownlie, C Garcia, G Cowan… - The Journal of …, 2016 - journals.aai.org
The cytoplasmic phosphatase, protein tyrosine phosphatase nonreceptor type 22 (PTPN22),
is a negative regulator of T cell signaling. Genome-wide association studies have shown …

Calcium/calmodulin signaling elicits release of cytochrome c during 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin-induced apoptosis in the human lymphoblastic T-cell line, L …

D Kobayashi, S Ahmed, M Ishida, S Kasai, H Kikuchi - Toxicology, 2009 - Elsevier
We have reported previously that 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) induces
apoptosis in the human lymphoblastic T-cell line L-MAT, although these cells do not express …

Role of endogenous annexin-A1 in the regulation of thymocyte positive and negative selection

N Paschalidis, A Huggins, NJ Rowbotham… - Cell Cycle, 2010 - Taylor & Francis
We have recently shown that endogenous Annexin-A1 (AnxA1) plays a homeostatic
regulatory role in mature T cells by modulating the strength of TCR signaling. In this study …

Bim regulates BCR‐induced entry of B cells into the cell cycle

A Craxton, KE Draves, EA Clark - European journal of …, 2007 - Wiley Online Library
Abstract BH3‐only Bcl‐2 homologs are key regulators of the intrinsic apoptotic pathway. In
particular, Bim, is critical for mediating apoptosis of hematopoietic cells including B cells …

IP3R function in cells of the immune system

AM Akimzhanov, D Boehning - Wiley Interdisciplinary Reviews …, 2012 - Wiley Online Library
Calcium ions regulate almost all cellular processes. Inositol 1, 4, 5‐trisphosphate receptors
(IP3Rs) are ubiquitous calcium channels which mediate calcium release primarily from …

Intracellular concentrations of Ca2+ modulate the strength of signal and alter the outcomes of cytotoxic T‐lymphocyte antigen‐4 (CD152)–CD80/CD86 interactions in …

A Ahmed, S Mukherjee, D Nandi - Immunology, 2009 - Wiley Online Library
The costimulatory receptors CD28 and cytotoxic T‐lymphocyte antigen (CTLA)‐4 and their
ligands, CD80 and CD86, are expressed on T lymphocytes; however, their functional roles …