The characterisation of subjective cognitive decline

F Jessen, RE Amariglio, RF Buckley… - The Lancet …, 2020 - thelancet.com
A growing awareness about brain health and Alzheimer's disease in the general population
is leading to an increasing number of cognitively unimpaired individuals, who are concerned …

Alzheimer's disease

JAS Lopez, HM González, GC Léger - Handbook of clinical neurology, 2019 - Elsevier
Alzheimer's disease (AD) dementia refers to a particular onset and course of cognitive and
functional decline associated with age together with a particular neuropathology. It was first …

Revised criteria for diagnosis and staging of Alzheimer's disease: Alzheimer's Association Workgroup

CR Jack Jr, JS Andrews, TG Beach… - Alzheimer's & …, 2024 - Wiley Online Library
Abstract The National Institute on Aging and the Alzheimer's Association convened three
separate work groups in 2011 and single work groups in 2012 and 2018 to create …

New insights into the genetic etiology of Alzheimer's disease and related dementias

C Bellenguez, F Küçükali, IE Jansen, L Kleineidam… - Nature …, 2022 - nature.com
Abstract Characterization of the genetic landscape of Alzheimer's disease (AD) and related
dementias (ADD) provides a unique opportunity for a better understanding of the associated …

[图书][B] Social isolation and loneliness in older adults: Opportunities for the health care system

National Academies of Sciences… - 2020 - books.google.com
Social isolation and loneliness are serious yet underappreciated public health risks that
affect a significant portion of the older adult population. Approximately one-quarter of …

Proteomics analysis of plasma from middle-aged adults identifies protein markers of dementia risk in later life

KA Walker, J Chen, L Shi, Y Yang, M Fornage… - Science translational …, 2023 - science.org
A diverse set of biological processes have been implicated in the pathophysiology of
Alzheimer's disease (AD) and related dementias. However, there is limited understanding of …

Alzheimer's disease–why we need early diagnosis

J Rasmussen, H Langerman - Degenerative neurological and …, 2019 - Taylor & Francis
Alzheimer's disease is the leading cause of dementia. However, neither Alzheimer's disease
nor Alzheimer's dementia are an inevitable consequence of aging. This review provides an …

NIA‐AA research framework: toward a biological definition of Alzheimer's disease

CR Jack Jr, DA Bennett, K Blennow… - Alzheimer's & …, 2018 - Wiley Online Library
Abstract In 2011, the National Institute on Aging and Alzheimer's Association created
separate diagnostic recommendations for the preclinical, mild cognitive impairment, and …

The complexity of Alzheimer's disease: an evolving puzzle

C Ferrari, S Sorbi - Physiological reviews, 2021 - journals.physiology.org
The history of Alzheimer's disease (AD) started in 1907, but we needed to wait until the end
of the century to identify the components of pathological hallmarks and genetic subtypes and …

Prevalence of depression, anxiety, and apathy symptoms across dementia stages: a systematic review and meta‐analysis

DKY Leung, WC Chan, A Spector… - International journal of …, 2021 - Wiley Online Library
Objective The present study aimed to resolve inconsistency in reported prevalence of
affective symptoms by dementia stage. Methods/Design We conducted a meta‐analysis of …