Targeting one‐carbon metabolism for cancer immunotherapy

X Ren, X Wang, G Zheng, S Wang… - Clinical and …, 2024 - Wiley Online Library
Abstract Background One‐carbon (1C) metabolism is a metabolic network that plays
essential roles in biological reactions. In 1C metabolism, a series of nutrients are used to …

[HTML][HTML] NLRP3 inflammasome: Pathogenic role and potential therapeutic target for IgA nephropathy

YL Tsai, KF Hua, A Chen, CW Wei, WS Chen… - Scientific Reports, 2017 - nature.com
We have previously showed that IL-1β is involved in the pathogenesis of both
spontaneously occurring and passively induced IgA nephropathy (IgAN) models. However …

Endurance training but not high-intensity interval training reduces liver carcinogenesis in mice with hepatocellular carcinogen diethylnitrosamine

X Zhang, L Cao, B Ji, L Li, Z Qi, S Ding - Experimental Gerontology, 2020 - Elsevier
Physical activity may reduce cancer initiation. High-intensity interval training (HIT) has been
reported to be superior to moderate continuous endurance training (ET) for maximizing …

[HTML][HTML] An exploratory gene expression study of the intestinal mucosa of patients with non-celiac wheat sensitivity

K Efthymakis, E Clemente, M Marchioni… - International Journal of …, 2020 - mdpi.com
Non-celiac wheat sensitivity (NCWS) is a recently recognized syndrome triggered by a
gluten-containing diet. The pathophysiological mechanisms engaged in NCWS are poorly …

The risk association of plasma total homocysteine with acute myocardial infarction is modified by serum vitamin A

T Olsen, KJ Vinknes, GFT Svingen… - European journal of …, 2018 - academic.oup.com
Background Plasma total homocysteine (tHcy) has been implicated in the development of
cardiovascular disease, but the mechanisms remain unclear. Vitamin A (Vit-A) is involved in …

[HTML][HTML] Elevated plasma cystathionine is associated with increased risk of mortality among patients with suspected or established coronary heart disease

I Dhar, V Lysne, GFT Svingen, PM Ueland… - The American journal of …, 2019 - Elsevier
Background Elevated circulating cystathionine levels are related to atherosclerotic
cardiovascular disease, a leading cause of death globally. Objective We investigated …

Proteomic changes by radio-mitigative thrombopoietin receptor agonist romiplostim in the blood of mice exposed to lethal total-body irradiation

T Nishida, M Yamaguchi, Y Tatara… - International Journal of …, 2020 - Taylor & Francis
Purpose The thrombopoietin receptor agonist romiplostim (RP) is a therapeutic agent for
immune thrombocytopenia that can achieve complete survival in mice exposed to a lethal …

Lipids, Homocysteine and Vitamin A: Perspectives and new hypotheses from patients with cardiovascular disease

T Olsen - 2020 - duo.uio.no
Vitamin A is an essential fat-soluble nutrient with important functions in growth, development
and the visual process. The major bioactive form of vitamin A, retinoic acid, can stimulate …