Blood–brain barrier dysfunction in the pathogenesis of major depressive disorder

S Wu, Y Yin, L Du - Cellular and Molecular Neurobiology, 2022 - Springer
Major depression represents a complex and prevalent psychological disease that is
characterized by persistent depressed mood, impaired cognitive function and complicated …

Major depressive disorder: hypothesis, mechanism, prevention and treatment

L Cui, S Li, S Wang, X Wu, Y Liu, W Yu… - … and Targeted Therapy, 2024 - nature.com
Worldwide, the incidence of major depressive disorder (MDD) is increasing annually,
resulting in greater economic and social burdens. Moreover, the pathological mechanisms …

[HTML][HTML] Amplitude of low-frequency fluctuation (ALFF) alterations in adults with subthreshold depression after physical exercise: a resting-state fMRI study

L Huang, G Huang, Q Ding, P Liang, C Hu… - Journal of affective …, 2021 - Elsevier
Background Physical exercise has been proved to reduce the risk of major depression in
Subthreshold depression (StD) individuals effectively, yet little is known about the …

Effects of exercise training on executive functioning in adults with depression: A systematic review and meta-analysis of randomized controlled trials

FF Ren, BL Alderman, WG Wang, FT Chen, WS Zhou… - Sports Medicine, 2023 - Springer
Background Exercise is a promising nonpharmacological intervention to improve executive
function (EF). However, results from randomized trials and meta-analyses examining the …

Exercise improves mental health status of young adults via attenuating inflammation factors but modalities matter

J Liu, Y Zhang, X Li, D Wang, B Shi, Y You… - Frontiers in …, 2022 - frontiersin.org
Introduction The mental health of young adults is a global public health challenge.
Numerous studies have demonstrated that exercise benefits mental health. However, it is …

[HTML][HTML] Manipulating reward sensitivity using reward circuit–targeted transcranial magnetic stimulation

J Ryan, JJ Pouliot, G Hajcak, DE Nee - Biological Psychiatry: Cognitive …, 2022 - Elsevier
Background The reward circuit is important for motivation and learning, and dysregulations
of the reward circuit are prominent in anhedonic depression. Noninvasive interventions that …

Neural responses to reward and pleasant pictures prospectively predict remission from depression.

J Klawohn, CJ Brush, G Hajcak - Journal of Abnormal Psychology, 2021 - psycnet.apa.org
Reduced neural responses to reward and pleasant stimuli—indicators of anhedonia and
reduced emotional reactivity, respectively—have been reported among individuals with …

Effects of aerobic exercise on event-related potentials related to cognitive performance: a systematic review

J Gusatovic, MH Gramkow, SG Hasselbalch… - PeerJ, 2022 - peerj.com
Objective To perform a systematic review on exercise intervention studies that use event-
related potentials (ERPs) as outcome for cognitive performance. Methods We identified …

[HTML][HTML] Effects of aerobic exercise on cognitive function in adults with major depressive disorder: A systematic review and meta-analysis

FF Ren, CH Hillman, WG Wang, RH Li, WS Zhou… - International journal of …, 2024 - Elsevier
Abstract Background Major Depressive Disorder (MDD) is a highly prevalent psychiatric
disorder that impairs the cognitive function of individuals. Aerobic exercise stands out as a …

Effects of virtual reality-based cognitive training for adolescents with depressive episodes: A pilot randomized controlled study

S Lyu, S Zhong, Y Luo, S Yan, H Ran, M Duan… - Psychiatry …, 2024 - Elsevier
Cognitive impairment is a common symptom in depression, yet few intervention strategies
target adolescents. This study investigated the effects of an attention and working memory …