Manganese (Mn) is an essential nutrient for intracellular activities; it functions as a cofactor
for a variety of enzymes, including arginase, glutamine synthetase (GS), pyruvate …

Zinc is involved in a variety of biological processes, as a structural, catalytic, and intracellular
and intercellular signaling component. Thus zinc homeostasis is tightly controlled at the …

Exposure to manganese (Mn) causes clinical signs and symptoms resembling, but not
identical to, Parkinson's disease. Since our last review on this subject in 2004, the past …

Zinc (Zn) is an essential trace mineral that regulates the expression and activation of
biological molecules such as transcription factors, enzymes, adapters, channels, and growth …

Iron is an essential element that is indispensable for life. The delicate physiological body
iron balance is maintained by both systemic and cellular regulatory mechanisms. The iron …

The understanding of manganese (Mn) biology, in particular its cellular regulation and role
in neurological disease, is an area of expanding interest. Mn is an essential micronutrient …

Manganese (Mn) is an essential heavy metal. However, Mn's nutritional aspects are
paralleled by its role as a neurotoxicant upon excessive exposure. In this review, we …

Essential metals are crucial for the maintenance of cell homeostasis. Among the 23
elements that have known physiological functions in humans, 12 are metals, including iron …

Manganese (Mn) is an essential trace element necessary for physiological processes that
support development, growth and neuronal function. Secondary to elevated exposure or …

Zinc is an essential micronutrient that plays a role in the structural or enzymatic functions of
many cellular proteins. Cellular zinc homeostasis involves the opposing action of two …