Mechanome-guided strategies in regenerative rehabilitation

D Jacho, E Yildirim-Ayan - Current Opinion in Biomedical Engineering, 2024 - Elsevier
Regenerative Rehabilitation represents a multifaceted approach that merges
mechanobiology with therapeutic intervention to harness the body's intrinsic tissue repair …

Peripheral blood transcriptomic analysis identifies potential inflammation and immune signatures for central retinal artery occlusion

J Feng, Y Li, C Wang, Y Wang, Y Wan, M Zheng… - Scientific Reports, 2024 - nature.com
Central retinal artery occlusion (CRAO) is an acute retinal ischaemic disease, but early
diagnosis is challenging due to a lack of biomarkers. Blood samples were collected from …

Deciphering the Cell-Specific Effect of Osteoblast-Macrophage Crosstalk in Periodontitis

D Jacho, P Babaniamansour, R Osorio… - … Engineering Part A, 2023 - liebertpub.com
In periodontitis, the bone remodeling process is disrupted by the prevalent involvement of
bacteria-induced proinflammatory macrophage cells and their interaction with osteoblast …

The Promise of Complement Therapeutics in Solid Organ Transplantation

JA Steggerda, PS Heeger - Transplantation, 2024 - journals.lww.com
Transplantation is the ideal therapy for end-stage organ failure, but outcomes for all
transplant organs are suboptimal, underscoring the need to develop novel approaches to …

Hedgehog costimulation during ischemia-reperfusion injury potentiates cytokine and homing responses of CD4+ T cells

S Wang, G Song, MN Barkestani, Z Tobiasova… - Frontiers in …, 2023 - frontiersin.org
Introduction Ischemia reperfusion injury (IRI) confers worsened outcomes and is an
increasing clinical problem in solid organ transplantation. Previously, we identified a …

不同冷冻技术对同种异体血管移植排斥反应的影响

龙俊东, 史业弘, 王成, 陈世玖 - 中国组织工程研究, 2024 - cjter.com
不同冷冻技术对同种异体血管移植排斥反应的影响 Page 1 Chinese Journal of Tissue
Engineering Research|Vol 28|No.3|January 2024|433 中国组织工程研究 Chinese Journal of …

Immune Evasive Stem Cell Islets

F Cuozzo, V Sordi, L Piemonti - Pluripotent Stem Cell Therapy for …, 2024 - Springer
Abstract Type 1 diabetes (T1D) is an autoimmune disease caused by the destruction of
insulin-secreting β cells by the immune system (American Diabetes, A., Diabetes Care 32 …

Enzymatic blood group conversion of human kidneys for transplantation

S MacMillan - 2024 - repository.cam.ac.uk
ABO blood group antigens present an immunological barrier in transplantation, restricting
organ donor-recipient matches to blood group compatible pairings only. Due to the chronic …

Pentraxin 3 in Kidney Disease and Renal Replacement Therapies

V Losappio, I Barbara, A Maiorano, S Simiele… - 2023 - preprints.org
Chronic kidney disease (CKD) is actually considered a public health priority according to the
increasing number of patients affected by this condition: this casuistry is not only related to …

Effects of different freezing techniques on the rejection of allogeneic vascular transplantation

J Long, Y Shi, C Wang, S Chen - Chinese Journal of Tissue Engineering …, 2024 - cjter.com
BACKGROUND: Cryopreservation can better ensure the integrity of the vascular structure.
How to reduce its immunogenicity to improve rejection after transplantation has attracted …