Assessment of glutathione/glutathione disulphide ratio and S-glutathionylated proteins in human blood, solid tissues, and cultured cells

D Giustarini, G Colombo, ML Garavaglia… - Free Radical Biology …, 2017 - Elsevier
Glutathione (GSH) is the major non-protein thiol in humans and other mammals, which is
present in millimolar concentrations within cells, but at much lower concentrations in the …

The nutraceuticals as modern key to achieve erythrocyte oxidative stress fighting in osteoarthritis

A Mariano, I Bigioni, F Misiti, L Fattorini… - Current issues in …, 2022 - mdpi.com
Osteoarthritis (OA), the most common joint disease, shows an increasing prevalence in the
aging population in industrialized countries. OA is characterized by low-grade chronic …

Senescence of primary amniotic cells via oxidative DNA damage

R Menon, I Boldogh, R Urrabaz-Garza, J Polettini… - PloS one, 2013 - journals.plos.org
Objective Oxidative stress is a postulated etiology of spontaneous preterm birth (PTB) and
preterm prelabor rupture of the membranes (pPROM); however, the precise mechanistic role …

Donor‐variation effect on red blood cell storage lesion: A close relationship emerges

VL Tzounakas, AG Kriebardis… - PROTEOMICS …, 2016 - Wiley Online Library
Although the molecular pathways leading to the progressive deterioration of stored red
blood cells (RBC storage lesion) and the clinical relevance of storage‐induced changes …

Oxidative damage in human gingival fibroblasts exposed to cigarette smoke

G Colombo, I Dalle-Donne, M Orioli, D Giustarini… - Free Radical Biology …, 2012 - Elsevier
Cigarette smoke, a complex mixture of over 7000 chemicals, contains many components
capable of eliciting oxidative stress, which may induce smoking-related disorders, including …

Role of protein carbonylation in skeletal muscle mass loss associated with chronic conditions

E Barreiro - Proteomes, 2016 - mdpi.com
Muscle dysfunction, characterized by a reductive remodeling of muscle fibers, is a common
systemic manifestation in highly prevalent conditions such as chronic heart failure (CHF) …

A central role for intermolecular dityrosine cross-linking of fibrinogen in high molecular weight advanced oxidation protein product (AOPP) formation

G Colombo, M Clerici, D Giustarini, N Portinaro… - … et Biophysica Acta (BBA …, 2015 - Elsevier
Background Advanced oxidation protein products (AOPPs) are dityrosine cross-linked and
carbonyl-containing protein products formed by the reaction of plasma proteins with …

Protective roles of honey in reproductive health: a review

SSM Zaid, SS Ruslee, MH Mokhtar - Molecules, 2021 - mdpi.com
Nowadays, most people who lead healthy lifestyles tend to use natural products as
supplements, complementary medicine or alternative treatments. Honey is God's precious …

Antioxidants in smokers

E Astori, ML Garavaglia, G Colombo… - Nutrition Research …, 2022 - cambridge.org
Cigarette smoke (CS) is likely the most common preventable cause of human morbidity and
mortality worldwide. Consequently, inexpensive interventional strategies for preventing CS …

Thiol oxidation and di-tyrosine formation in human plasma proteins induced by inflammatory concentrations of hypochlorous acid

G Colombo, M Clerici, A Altomare, F Rusconi… - Journal of …, 2017 - Elsevier
In this study, we assessed the oxidative damage occurring in plasma proteins when human
blood was exposed to inflammatory concentrations of hypochlorous acid (HOCl). We used …