Brain and cognition for addiction medicine: From prevention to recovery neural substrates for treatment of psychostimulant-induced cognitive deficits

MS D'Souza - Frontiers in psychiatry, 2019 - frontiersin.org
Addiction to psychostimulants like cocaine, methamphetamine, and nicotine poses a
continuing medical and social challenge both in the United States and all over the world …

Achieving smoking cessation among persons with opioid use disorder

C Vlad, JH Arnsten, S Nahvi - CNS drugs, 2020 - Springer
While prevalence of tobacco use in the US general population is declining, prevalence
among those with opioid use disorder (OUD) remains high and results in excessive tobacco …

Central nicotine induces browning through hypothalamic κ opioid receptor

P Seoane-Collazo, L Liñares-Pose… - Nature …, 2019 - nature.com
Increased body weight is a major factor that interferes with smoking cessation. Nicotine, the
main bioactive compound in tobacco, has been demonstrated to have an impact on energy …

Longitudinal associations between age 20 problematic substance use and opioid use disorder incidence at age 30–findings from an urban cohort

J Thrul, JA Rabinowitz, BA Reboussin… - Journal of psychiatric …, 2023 - Elsevier
This study used data from a longitudinal prevention study in an urban cohort to examine
associations between nicotine dependence, alcohol, and cannabis use disorder and …

Traumatic stress-induced vulnerability to addiction: critical role of the dynorphin/kappa opioid receptor system

C Leconte, R Mongeau, F Noble - Frontiers in Pharmacology, 2022 - frontiersin.org
Substance use disorders (SUD) may emerge from an individual's attempt to limit negative
affective states and symptoms linked to stress. Indeed, SUD is highly comorbid with chronic …

Understanding the implications of the biobehavioral basis of nicotine addiction and its impact on the efficacy of treatment

N Bozinoff, B Le Foll - Expert review of respiratory medicine, 2018 - Taylor & Francis
Introduction: Tobacco use remains the leading cause of preventable death in the United
States. There are efficacious behavioral and pharmacological options for smoking cessation …

Elucidating the reinforcing effects of nicotine: a tribute to Nadia Chaudhri

AF Sved, AR Caggiula, EC Donny - Psychopharmacology, 2023 - Springer
Nadia Chaudhri worked with us as a graduate student in the Center for Neuroscience at the
University of Pittsburgh from 1999 until she earned her PhD in 2005, a time that coincided …

[HTML][HTML] Reward processing in schizophrenia and its relation to Mu opioid receptor availability and negative symptoms: A [11C]-carfentanil PET and fMRI study

E Shatalina, AH Ashok, MB Wall, MM Nour, J Myers… - NeuroImage: Clinical, 2023 - Elsevier
Background Reward processing deficits are a core feature of schizophrenia and are thought
to underlie negative symptoms. Pre-clinical evidence suggests that opioid …

Altered mrna levels of stress-related peptides in mouse hippocampus and caudate-putamen in withdrawal after long-term intermittent exposure to tobacco smoke or …

L Carboni, L Ponzoni, D Braida, M Sala, C Gotti… - International Journal of …, 2021 - mdpi.com
Nicotine addiction is a severe public health problem. The aim of this study was to investigate
the alterations in key neurotransmissions after 60 days of withdrawal from seven weeks of …

Opioid and nondopamine reward circuitry and state‐dependent mechanisms

M Fujita, S Ide, K Ikeda - Annals of the New York Academy of …, 2019 - Wiley Online Library
A common notion is that essentially all addictive drugs, including opioids, activate
dopaminergic pathways in the brain reward system, and the inappropriate use of such drugs …