Wildlife ecological risk assessment in the 21st century: Promising technologies to assess toxicological effects

BA Rattner, TG Bean, VR Beasley… - Integrated …, 2024 - Wiley Online Library
Despite advances in toxicity testing and the development of new approach methodologies
(NAMs) for hazard assessment, the ecological risk assessment (ERA) framework for …

[HTML][HTML] Ionophore coccidiostats–disposition kinetics in laying hens and residues transfer to eggs

A Bello, J Henri, A Viel, JP Mochel, B Poźniak - Poultry Science, 2023 - Elsevier
Poultry production is linked with the use of veterinary medicinal products to manage
diseases. Ionophore coccidiostats have been permitted for use as feed additives within the …

In silico environmental risk assessment improves efficiency for pesticide safety management

YY Gao, W Zhao, YQ Huang, V Kumar, X Zhang… - Science of The Total …, 2024 - Elsevier
Pesticides are indispensable to maintain crop quality and food production worldwide, but
their use also poses environmental risks. Pesticide risk assessment involves a series of …

Toxicological effects assessment for wildlife in the 21st century: Review of current methods and recommendations for a path forward

TG Bean, VR Beasley, P Berny… - Integrated …, 2024 - Wiley Online Library
Abstract Model species (eg, granivorous gamebirds, waterfowl, passerines, domesticated
rodents) have been used for decades in guideline laboratory tests to generate survival …

Cross‐species extrapolation of biological data to guide the environmental safety assessment of pharmaceuticals—The state of the art and future priorities

L Margiotta‐Casaluci, SF Owen… - Environmental …, 2024 - Wiley Online Library
The extrapolation of biological data across species is a key aspect of biomedical research
and drug development. In this context, comparative biology considerations are applied with …

[HTML][HTML] Physiologically based kinetic (PBK) modeling of propiconazole using a machine learning-enhanced read-across approach for interspecies extrapolation

Y Wu, G Sinclair, R Avanasi, A Pecquet - Environment International, 2024 - Elsevier
A significant challenge in the traditional human health risk assessment of agrochemicals is
the uncertainty in quantifying the interspecies differences between animal models and …

Interspecies scaling of toxicity reference values in human health versus ecological risk assessments: A critical review

HJ Clewell, PC Fuchsman - … Environmental Assessment and …, 2024 - Wiley Online Library
Risk assessments that focus on anthropogenic chemicals in environmental media—whether
considering human health or ecological effects—often rely on toxicity data from …

An overview of physiologically-based pharmacokinetic models for forensic science

K Fairman, MK Choi, P Gonnabathula, A Lumen… - Toxics, 2023 - mdpi.com
A physiologically-based pharmacokinetic (PBPK) model represents the structural
components of the body with physiologically relevant compartments connected via blood …

[HTML][HTML] Development of a mechanistic model for analyzing avian reproduction data for pesticide risk assessment

M Trijau, B Goussen, R Brain, J Maul, N Galic - Environmental Pollution, 2023 - Elsevier
Mechanistic effect models are increasingly recommended as tools for refining evaluations of
risk from exposure to pesticides. In the context of bird and mammal risk assessments, DEB …

A comprehensive study of liver-gut microbiota and antioxidant enzyme activity mediated regulation of late-laying hens by high and low residual feed intake

Z Gao, C Zheng, Z Mao, J Zheng, G Xu, D Liu - International Journal of …, 2025 - Elsevier
Residual feed intake (RFI) is a better indicator of feed efficiency than feed conversion ratio
(FCR). It is frequently used to evaluate the efficacy of poultry and livestock feed …