[HTML][HTML] Neurofibromatosis 1

JM Friedman - 2022 - europepmc.org
Neurofibromatosis 1 (NF1) is a multisystem disorder characterized by multiple café au lait
macules, intertriginous freckling, multiple cutaneous neurofibromas, and learning disability …

Neurofibromatosis Type 1-associated optic pathway gliomas: Current challenges and future prospects

Y Tang, DH Gutmann - Cancer Management and Research, 2023 - Taylor & Francis
Optic pathway glioma (OPG) occurs in as many as one-fifth of individuals with the
neurofibromatosis type 1 (NF1) cancer predisposition syndrome. Generally considered low …

Pediatric low-grade glioma: state-of-the-art and ongoing challenges

J Fangusaro, DT Jones, RJ Packer… - Neuro …, 2024 - academic.oup.com
The most common childhood central nervous system (CNS) tumor is pediatric low-grade
glioma (pLGG), representing 30%–40% of all CNS tumors in children. Although there is high …

Optic pathway glioma in type 1 neurofibromatosis: review of its pathogenesis, diagnostic assessment, and treatment recommendations

M Cassina, L Frizziero, E Opocher, R Parrozzani… - Cancers, 2019 - mdpi.com
Type 1 neurofibromatosis (NF1) is a dominantly inherited condition predisposing to tumor
development. Optic pathway glioma (OPG) is the most frequent central nervous system …

Frequency of pathogenic germline variants in cancer-susceptibility genes in the Childhood Cancer Survivor Study

J Kim, M Gianferante, DM Karyadi… - JNCI Cancer …, 2021 - academic.oup.com
Background Pediatric cancers are the leading cause of death by disease in children despite
improved survival rates overall. The contribution of germline genetic susceptibility to …

Treatment and outcome in 65 children with optic pathway gliomas

MA El Beltagy, M Reda, A Enayet, MS Zaghloul… - World Neurosurgery, 2016 - Elsevier
Introduction Optic pathway gliomas (OPGs) are rare neoplasms in children with an
unpredictable clinical course. There is significant controversy regarding the optimal …

Management of optic pathway glioma: a systematic review and meta-analysis

O Yousefi, P Azami, M Sabahi, R Dabecco, B Adada… - Cancers, 2022 - mdpi.com
Simple Summary In the current study, we systematically reviewed the literature regarding the
management of optic pathway glioma (OPG). This review will analyze demographics …

Brachytherapy of intracranial gliomas

SB Nachbichler, FW Kreth - Intracranial Gliomas Part II-Adjuvant …, 2018 - karger.com
Interstitial implantation of radioactive materials (brachytherapy [BT]) has been designed to
protractedly deliver a high radiation dose to a well-defined target volume, while minimizing …

Phakomatoses

B Becker, RE Strowd - Dermatologic clinics, 2019 - derm.theclinics.com
The phakomatoses are a heterogenous group of clinical syndromes characterized by
cutaneous, neurologic, and oncologic manifestations. These neurocutaneous syndromes …

Nonneuroendocrine neoplasms of the pituitary region

GA Kaltsas, D Kolomodi, H Randeva… - The Journal of Clinical …, 2019 - academic.oup.com
Context Although most sellar lesions are related to pituitary adenomas, the region gives rise
to a variety of neoplasms that can be associated with substantial morbidity and/or mortality …