[HTML][HTML] Interactions of analgesics with cisplatin: Modulation of anticancer efficacy and potential organ toxicity

A El-Sheikh, Z Khired - Medicina, 2021 - mdpi.com
Cisplatin (CDDP), one of the most eminent cancer chemotherapeutic agents, has been
successfully used to treat more than half of all known cancers worldwide. Despite its …

Natural Products Reverse Cisplatin Resistance in the Hypoxic Tumor Microenvironment

C Yang, X Deng, Y Tang, H Tang, C Xia - Cancer Letters, 2024 - Elsevier
Cisplatin is one of the most commonly used drugs for cancer treatment. Despite much
progress in improving patient outcomes, many patients are resistant to cisplatin-based …

[HTML][HTML] Hesperidin protects against cisplatin-induced cardiotoxicity in mice by regulating the p62–Keap1–Nrf2 pathway

Y Jia, H Guo, X Cheng, Y Zhang, M Si, J Shi, D Ma - Food & Function, 2022 - pubs.rsc.org
Hesperidin (HES) is an abundant and economical dietary bioflavonoid, and it has several
pharmacological properties such as antioxidant activity and powerful cardiac protection …

Cisplatin cycles treatment sustains cardiovascular and renal damage involving TLR4 and NLRP3 pathways

A González, S García‐Gómez‐Heras… - Pharmacology …, 2023 - Wiley Online Library
Cisplatin is clinically proven to combat different cancers, including sarcomas, soft tissue
cancers, bones, muscles, and blood. However, renal and cardiovascular toxicities are …

Molecular mechanisms involved in therapeutic effects of natural compounds against cisplatin-induced cardiotoxicity: a review

M Hesari, P Mohammadi, M Moradi… - Naunyn-Schmiedeberg's …, 2024 - Springer
Cisplatin is a widely used chemotherapeutic agent for the treatment of various cancers.
However, the clinical use of cisplatin is limited by its cardiotoxic side effects. The primary …

Investigation of the protective effect of selenium supplementation on renal function in cisplatin-administered rats

M Altunkaya, G Abuşoğlu, B Ozturk - Cukurova Medical Journal, 2024 - dergipark.org.tr
Purpose: Selenium is an important antioxidant and anticarcinogen with the ability to protect
cells from oxidative stress, a significant marker of cisplatin-induced toxicity. This study aimed …