Bioprinting 101: design, fabrication, and evaluation of cell-laden 3D bioprinted scaffolds
3D bioprinting is an additive manufacturing technique that recapitulates the native
architecture of tissues. This is accomplished through the precise deposition of cell …
architecture of tissues. This is accomplished through the precise deposition of cell …
Beyond appetite regulation: Targeting energy expenditure, fat oxidation, and lean mass preservation for sustainable weight loss
BØ Christoffersen, G Sanchez‐Delgado, LM John… - …, 2022 - Wiley Online Library
New appetite‐regulating antiobesity treatments such as semaglutide and agents under
investigation such as tirzepatide show promise in achieving weight loss of 15% or more …
investigation such as tirzepatide show promise in achieving weight loss of 15% or more …
Resveratrol supplementation of high‐fat diet‐fed pregnant mice promotes brown and beige adipocyte development and prevents obesity in male offspring
Key points Maternal high‐fat diet impairs brown adipocyte function and correlates with
obesity in offspring. Maternal resveratrol administration recovers metabolic activity of …
obesity in offspring. Maternal resveratrol administration recovers metabolic activity of …
The colorful versatility of adipocytes: white‐to‐brown transdifferentiation and its therapeutic potential in humans
Brown and brite adipocytes contribute to energy expenditure through nonshivering
thermogenesis. Though these cell types are thought to arise primarily from the de novo …
thermogenesis. Though these cell types are thought to arise primarily from the de novo …
[HTML][HTML] Stem-cell based organ-on-a-chip models for diabetes research
Diabetes mellitus (DM) ranks among the severest global health concerns of the 21st century.
It encompasses a group of chronic disorders characterized by a dysregulated glucose …
It encompasses a group of chronic disorders characterized by a dysregulated glucose …
LSD1 interacts with Zfp516 to promote UCP1 transcription and brown fat program
Zfp516, a brown fat (BAT)-enriched and cold-inducible transcription factor, promotes
transcription of UCP1 and other BAT-enriched genes for non-shivering thermogenesis …
transcription of UCP1 and other BAT-enriched genes for non-shivering thermogenesis …
Fat-on-a-chip models for research and discovery in obesity and its metabolic comorbidities
M McCarthy, T Brown, A Alarcon… - … Engineering Part B …, 2020 - liebertpub.com
The obesity epidemic and its associated comorbidities present a looming challenge to
health care delivery throughout the world. Obesity is characterized as a sterile inflammatory …
health care delivery throughout the world. Obesity is characterized as a sterile inflammatory …
[HTML][HTML] Hyaluronan in adipogenesis, adipose tissue physiology and systemic metabolism
Hyaluronic acid (HA, also known as hyaluronan), is a non-sulfated linear glycosaminoglycan
polymer consisting of repeating disaccharide units of d-glucuronic acid and N-acetyl-d …
polymer consisting of repeating disaccharide units of d-glucuronic acid and N-acetyl-d …
Matrix metalloproteinase-13 mediated degradation of hyaluronic acid-based matrices orchestrates stem cell engraftment through vascular integration
A critical design parameter for the function of synthetic extracellular matrices is to
synchronize the gradual cell-mediated degradation of the matrix with the endogenous …
synchronize the gradual cell-mediated degradation of the matrix with the endogenous …
Adrenergic regulation of cellular plasticity in brown, beige/brite and white adipose tissues
VD Ramseyer, JG Granneman - Adipocyte, 2016 - Taylor & Francis
The discovery of brown adipose tissue in adult humans along with the recognition of
adipocyte heterogeneity and plasticity of white fat depots has renewed the interest in …
adipocyte heterogeneity and plasticity of white fat depots has renewed the interest in …